Evidence map›Paper›PMID 40055806›Full record

ArticleBMC research notes2025

How much does it cost to retain clients on antiretroviral treatment for one year in a large, public clinic? Routine financial costs of retention interventions at Lighthouse Trust in Lilongwe, Malawi.

Hiwot Weldemariam, Agness Thawani, Christine Kiruthu-Kamamia, Jacqueline Huwa, Mirriam Chipanda, Hannock Tweya, Caryl Feldacker

Abstract read
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Hiwot WeldemariamDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
Agness ThawaniLighthouse Trust, Lilongwe, Malawi.
Christine Kiruthu-KamamiaLighthouse Trust, Lilongwe, Malawi.
Jacqueline HuwaLighthouse Trust, Lilongwe, Malawi.
Mirriam ChipandaLighthouse Trust, Lilongwe, Malawi.
Hannock TweyaInternational Training and Education Center for Health, Seattle, WA, USA.
Caryl FeldackerInternational Training and Education Center for Health, Seattle, WA, USA. cfeld@uw.edu.

Funding

Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
Two-way Texting (2wT) to Improve Patient Retention While Reducing the Healthcare Workload in High-Burden Public HIV Clinics in MalawiR33TW011658 · FIC · UNIVERSITY OF WASHINGTON · PI O'MALLEY, GABRIELLE · 2022 to 2024
$1.1M
Two-way Texting (2wT) to Improve Patient Retention While Reducing the Healthcare Workload in High-Burden Public HIV Clinics in MalawiR21TW011658 · FIC · UNIVERSITY OF WASHINGTON · PI FELDACKER, CARYL · 2020 to 2021
$391k
FIC NIH HHS D43 TW010060FIC NIH HHS R21 TW011658FIC NIH HHS R33 TW011658NIH HHS R21TW011658/R33TW011658
6 · The paper itself

Abstract

introductionPoor retention (missed appointments or treatment discontinuation) on antiretroviral therapy (ART) may lead to disease progression, increased mortality, and HIV transmission. This study quantified the financial costs of implementing 12 months of routine services to improve ART retention at a large public clinic in Lilongwe, Malawi.

methodsWe performed activity-based micro-costing from the payer perspective using routine program data to assess the costs associated with two retention interventions: ART treatment buddies (expert clients) and Back-to-Care (B2C) tracing services. New ART initiates receive a Buddy who provides proactive retention support for 12 months. B2C traces all clients who miss ART visits by ≥ 14 days. Costs were calculated as total and per-client expenditures, reported in 2021 USD.

resultsThe total cost for 12 months of ART retention activities was $237,564. Buddies accounted for $108,504, with personnel costs contributing $97,764. B2C totaled $129,060, with personnel expenses remaining substantial at $73,778. The unit costs were $34 per client Buddy and $17 per B2C tracing event.

conclusionThis study highlights the financial costs of delivering 12 months of ART retention services at a public, low-resource clinic. While proactive and reactive retention strategies are costly, both are essential for engaging ART clients from initiation onward.

Indexed as

Ambulatory Care FacilitiesAnti-HIV AgentsAnti-Retroviral AgentsHealth Care CostsHIV InfectionsRetention in CareFemaleHumansMalawiMaleAnti-HIV AgentsAnti-Retroviral AgentsActivity-based costingCost of routine health interventionsMalawiPatient tracingPrevention of treatment interruptionRetention in antiretroviral therapy care

Identifiers

PMID40055806
PMCPMC11889891

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.