Evidence map›Paper›PMID 40055754›Full record

ArticleBMC oral health2025

Evaluation of the effect of new generation denture base materials aged in artificial saliva at different pH levels on surface roughness and Candida albicans adhesion.

Ezgi Arslan, Canan Akay, Demet Erdönmez, Esra Nur Avukat

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ezgi ArslanDepartment of Prosthodontics, Faculty of Dentistry, Eskisehir Osmangazi University, Eskisehir, Türkiye. ezgidurmus72@gmail.com.ORCID http://orcid.org/0000-0002-2372-3047
Canan AkayDepartment of Prosthodontics, Faculty of Dentistry, Eskisehir Osmangazi University, Eskisehir, Türkiye.ORCID http://orcid.org/0000-0003-2781-8710
Demet ErdönmezDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Düzce University, Düzce, Türkiye.ORCID http://orcid.org/0000-0002-5331-2206
Esra Nur AvukatDepartment of Prosthodontics, Faculty of Dentistry, Eskisehir Osmangazi University, Eskisehir, Türkiye.ORCID http://orcid.org/0000-0003-0533-8994

Funding

Eskisehir Osmangazi University Scientific Research Projects TDH-2023-2605
6 · The paper itself

Abstract

purposeThe aim of this in vitro study was to evaluate the surface roughness and Candida albicans (C. albicans) biofilm formation of conventional heat-cured and different CAD/CAM milling denture base materials, after immersion in different pH levels of artificial saliva. MATERIALS AND

methodsDisc-shaped samples (10 × 2 mm) (n = 10) were prepared from two brands of CAD/CAM milled and conventional heat-cured PMMA denture base materials. The samples were immersed at 37 °C for 21 days in different pH levels of artificial saliva. The surface roughness (Ra) of each sample was measured using a contact profilometer before and after aging. C. albicans adhesion of the samples was determined using the Crystal Violet (CV) method.

resultsA significant increase in roughness was observed across all material groups maintained at pH 3 (P < 0.001). At pH 7, the roughness for heat-cured PMMA and G-PMMA groups increased significantly. Although pH 14 increased roughness in all groups, this was not significant. Upon comparison of roughness values post-aging, no significant differences were noted between the groups at pH 3 and pH 7; however, the G-PMMA group exhibited significantly lower surface roughness at pH 14 (P < 0.05). Among all material groups, the highest adhesion of C. albicans was observed in the heat-cured PMMA group. (P < 0.05).

conclusionsAging at different pH values caused surface changes in denture base materials and differences in C. albicans adhesion. Although there is an increase in surface roughness in all groups, these values are lower than the plaque accumulation threshold. The highest C. albicans adhesion was observed in heat-cured PMMA samples. Considering both roughness values and Candida adhesions, it is concluded that the new generation denture base materials are suitable for clinical use and should be widely used.

Indexed as

Candida albicansDental MaterialsDenture BasesSaliva, ArtificialBiofilmsCell AdhesionGentian VioletHumansHydrogen-Ion ConcentrationMaterials TestingPolymethyl MethacrylateSurface PropertiesDental MaterialsGentian VioletPolymethyl MethacrylateSaliva, ArtificialBiofilm formationCAD/CAMCandida albicansCrystal violetPMMA

Identifiers

PMID40055754
PMCPMC11889897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.