ArticleLipids in health and disease2025
The ratio of perirenal fat thickness to renal parenchymal thickness, a novel indicator of fat accumulation associated with kidney stones.
Article in Lipids in health and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Association between sarcopenic obesity and kidney stones: evidence from a prospective cohort study on the UK Biobank.BMC public health · 2026Article
- A cross-sectional and bioinformatics-based analysis: perirenal fat thickness as a superior predictor of kidney stone disease.Lipids in health and disease · 2025Article
- Opportunistic Detection of Chronic Kidney Disease Using CT-Based Measurements of Kidney Volume and Perirenal Fat.Journal of clinical medicine · 2025Article
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7 authors.
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Abstract
backgroundMetabolic syndrome, identified by increased visceral fat accumulation, is notably linked to a heightened risk of nephrolithiasis. Despite this, the influence of the perirenal fat thickness relative to renal parenchymal thickness on kidney stones (KS) development remains ambiguous. This study investigated the clinical characteristics of perirenal fat on both the left and right sides and explored the association between the aforementioned ratio and KS.
methodsThe study enrolled 161 participants who underwent computed tomography (CT) scans. In this study, kidneys were segregated into two categories based on the presence of stones: stone-bearing and non-stone-bearing for both the left and right kidneys. Perirenal fat parameters were extracted from the imaging workstation database. Both univariate and multivariate logistic regression analyses were conducted to explore the correlation between metrics related to perirenal fat and the occurrence of KS.
resultsAmong the 161 participants, significant variations in perirenal fat were observed between the left and right kidneys, as well as between genders. Subsequent to adjustments for several confounding variables, the multivariable logistic regression model demonstrated a significant correlation between the ratio of perirenal fat thickness to renal parenchymal thickness and stone bearing kidney (P < 0.001).
conclusionsThe ratio of perirenal fat thickness to renal parenchymal thickness was significantly correlated with kidney stones.
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