ArticleBMC public health2025
Evaluating community knowledge of tuberculosis preventive therapy in rural South Africa.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Tuberculosis prevention in children, adolescents, and pregnant and postpartum women in South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026Article
- Application of causal forest double machine learning (DML) approach to assess tuberculosis preventive therapy's impact on ART adherence.Scientific reports · 2025Article
- Toward community-driven tuberculosis education: findings from a knowledge and engagement pilot survey in the rural community of Eastern Cape, South Africa.Frontiers in public health · 2025Article
- Assessing awareness of latent tuberculosis infection: the urgent need for clinical governance-driven education in rural Eastern Cape - insights from a community-based study.Frontiers in public health · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundTuberculosis preventive therapy (TPT) effectively reduces TB incidence among people living with HIV, but implementation remains suboptimal and data on community knowledge of TPT is needed. We sought to understand community members' knowledge of TB and TPT to facilitate implementation of TPT.
methodsIn rural Msinga, KwaZulu Natal, South Africa, a cross-sectional study was conducted at community events during an HIV and TB testing initiative. Participants ≥ 18 years old who were residents of Msinga were anonymously surveyed. We evaluated Knowledge of TB and TPT, generating separate scores for each domain. Descriptive statistics, chi-square testing, Kruskal-Wallis, linear regression, and exploratory factor analysis (EFA) were performed.
resultsAmong 104 respondents, median age was 32.5 years, 65% were female, and 23% completed secondary school. EFA identified two factors for TB knowledge: cultural beliefs of TB's origin and transmission and understanding TB as a disease. Overall, TB knowledge was poor (median 10, IQR 8-12.5). Over one-third (N = 39, 37.5%) were unaware of TPT. Those who had heard of TPT had good knowledge of TPT, with a median score of 4 (IQR 4-4) out of 4. Factors associated with higher TPT knowledge on multivariate linear regression included being motivated to stay healthy to care for one's family and knowing that TB can be avoided.
conclusionsRural South African community members demonstrated poor TB knowledge. Community members with good knowledge of TB were also aware of TPT. Greater community-level public health education and individual-level counseling efforts are needed to facilitate TPT expansion and implementation.
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