Evidence map›Paper›PMID 40055344›Full record

ArticleNature communications2025

Locomotion-dependent auditory gating to the parietal cortex guides multisensory decisions.

Ilsong Choi, Seung-Hee Lee

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Parietal cortex is causally required for state-dependent decisions.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ilsong ChoiCenter for Synaptic Brain Dysfunctions, IBS, Daejeon, 34141, Republic of Korea.
Seung-Hee LeeCenter for Synaptic Brain Dysfunctions, IBS, Daejeon, 34141, Republic of Korea. shlee1@kaist.ac.kr.ORCID http://orcid.org/0000-0002-9486-5771

Funding

National Research Foundation of Korea (NRF) NRF-2021R1A2C3012159
6 · The paper itself

Abstract

Decision-making in mammals fundamentally relies on integrating multiple sensory inputs, with conflicting information resolved flexibly based on a dominant sensory modality. However, the neural mechanisms underlying state-dependent changes in sensory dominance remain poorly understood. Our study demonstrates that locomotion in mice shifts auditory-dominant decisions toward visual dominance during audiovisual conflicts. Using circuit-specific calcium imaging and optogenetic manipulations, we found that weakened visual representation in the posterior parietal cortex (PPC) leads to auditory-dominant decisions in stationary mice. Prolonged locomotion, however, promotes visual dominance by inhibiting auditory cortical neurons projecting to the PPC (AC

Indexed as

Auditory CortexAuditory PerceptionDecision MakingLocomotionParietal LobeSensory GatingAcoustic StimulationAnimalsFemaleMaleMiceMice, Inbred C57BLMotor CortexNeuronsOptogeneticsPhotic Stimulation

Identifiers

PMID40055344
PMCPMC11889129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.