Evidence map›Paper›PMID 40054959›Full record

ArticleJACC. Case reports2025

Acute Rheumatic Fever in a Low Prevalence Setting.

Mark Coyle, Aimee McGreal, John McCormick, Oisin Galvin, Angela McInerney, Andrea Holmes, Yvonne Smyth

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mark CoyleDepartment of Cardiology, Galway University Hospital, Galway, Ireland. Electronic address: Mark.coyle2@hse.ie.
Aimee McGrealDepartment of Infectious Diseases, Galway University Hospital, Galway, Ireland.
John McCormickDepartment of Cardiology, Galway University Hospital, Galway, Ireland.
Oisin GalvinDepartment of Cardiology, Galway University Hospital, Galway, Ireland.
Angela McInerneyDepartment of Cardiology, Galway University Hospital, Galway, Ireland.
Andrea HolmesDepartment of Infectious Diseases, Galway University Hospital, Galway, Ireland.
Yvonne SmythDepartment of Cardiology, Galway University Hospital, Galway, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute rheumatic fever is a systemic inflammatory condition caused by beta-hemolytic streptococcal infection. Its prevalence in high-income countries has fallen significantly as a result of widespread antibiotic use and improved living conditions. CASE SUMMARY: We report the case of an 18-year-old, otherwise healthy, Irish woman who presented to an Irish hospital with fever and general malaise on a background of recurrent pharyngitis. Her condition rapidly deteriorated in the hospital and she developed septic shock requiring intensive care admission for organ support. Investigations confirmed pancarditis secondary to acute rheumatic fever, which was ultimately treated with antibiotics and corticosteroids. DISCUSSION: This case highlights that acute rheumatic fever can present with multiple nonspecific symptoms, in unexpected populations, including in the developed world. Early diagnosis and treatment initiation of antimicrobial therapy and corticosteroids is imperative for optimal overall outcomes in rheumatic heart disease.

Indexed as

acute heart failuremitral valverheumatic heart disease

Identifiers

PMID40054959
PMCPMC11911856

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.