Evidence map›Paper›PMID 40054903›Full record

ArticleJACC. Case reports2025

Obstructive Shock Caused by Intimal Sarcoma With Pulmonary Vein Stenosis and SVC/IVC Obstruction.

Ebenezer Daniel, Jesu Krupa, Anne Jennifer Prabhu, Leena Robinson Vimala, Viji Samuel Thomson

Abstract read
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Left atrial primary intimal sarcoma mimicking myxoma: case report.European heart journal. Case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ebenezer DanielDepartment of Cardiology, Christian Medical College, Vellore, India. Electronic address: ebenezer.daniel@cmcvellore.ac.in.
Jesu KrupaDepartment of Cardiology, Christian Medical College, Vellore, India.
Anne Jennifer PrabhuDepartment of Pathology, Christian Medical College, Vellore, India.
Leena Robinson VimalaDepartment of Radiology, Christian Medical College, Vellore, India.
Viji Samuel ThomsonDepartment of Cardiology, Christian Medical College, Vellore, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 63-year-old woman presented with worsening dyspnea. Imaging revealed a right atrial mass extending to the left atrium, pulmonary veins, and vena cavae. Biopsy showed spindle-shaped cells with pleomorphism and high mitotic activity. Immunohistochemistry showed positive staining for SMA, desmin, and MDM2, supporting a diagnosis of intimal sarcoma. Due to the tumor's inoperability, she was offered palliative care. The tumour rapidly progressed, leading to pulmonary vein stenosis and obstruction of the vena cavae, leading to obstructive shock. This case illustrates the aggressive nature of intimal sarcomas, which present with local infiltration and obstructive symptoms.

Indexed as

cardiac sarcomacardio-oncology, inferior vena cava (IVC) obstructionintimal sarcomaMDM2 amplificationpulmonary vein stenosissuperior vena cava (SVC) obstruction

Identifiers

PMID40054903
PMCPMC11911864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.