SynthesisAmerican journal of preventive medicine2025
Allostatic Load and Cardiovascular Disease: A Systematic Review.
Synthesis in American journal of preventive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- A randomized, double-blind, crossover study of acute low-level night-time road traffic noise: effects on vascular function, sleep, and proteomic signatures in healthy adults.Cardiovascular research · 2026Trial
- Psychometric Evidence for Chronic Stress Patient-Reported Outcome Measures in African American Adults: An Equity-Focused COSMIN Systematic Review.Journal of racial and ethnic health disparities · 2026Review
- A systematic review and empiric examination of the conceptual and analytic overlap between allostatic load and multimorbidity.SSM - population health · 2026Article
- Genomic structural equation modeling elucidates the genetic mechanisms underlying allostatic load.Comprehensive psychoneuroendocrinology · 2026Article
- Association between cumulative biological risk and hypertension in older adults in Korea: a population-based cross-sectional study.Journal of Korean biological nursing science · 2026Article
- Does time heal all wounds? Examining the lasting impact of historic redlining on contemporary racial disparities in allostatic load in Baltimore, Maryland.Ethnicity & health · 2026Article
- From Molecules to Meaning: Integrating Neuropeptides, Sociostasis, and Hormesis in the Brain-Heart Axis.Current issues in molecular biology · 2026Review
- Examining the Association Between Occupational Strain and Risk of Angina Pectoris Among Older Working Adults in India Using Karasek's Job Demand Control Model.Research square · 2026Article
- Allostatic Load and Healthcare Access Among Stroke Survivors.Journal of racial and ethnic health disparities · 2026Article
- Article
- Comparative Evaluation of Metabolic Syndrome, Circadian Syndrome, and Allostatic Load Measures on All-Cause Mortality in U.S. Males and Females.International journal of endocrinology · 2026Article
- Phenotypic Age Acceleration as a Mediator in Thyroid Hormone-Related Cardiovascular Risk Among the Elderly.Cardiology research and practice · 2026Article
- Higher allostatic load at hospitalization is linked to worse outcome 90 days after stroke.Frontiers in stroke · 2026Article
- Article
- Labour-type physical activity, alcohol use and hypertension in rural older adults in Northeast China.Frontiers in public health · 2026Article
- Echoes of Inequity: A Critical Examination of the Past, Present, and Future of Cardiac Health Equity.Current cardiology reports · 2025Review
- Intersecting race/ethnicity and gender in physiological dysregulation profiles and associations with socioeconomic status among older adults in the United States.SSM - population health · 2025Article
- Allostatic load index in patients with pituitary tumours: a case control study.Frontiers in endocrinology · 2025Article
- Environmental and social determinants of cardiovascular risk in women with type 2 diabetes: a life-course perspective.Frontiers in endocrinology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionCardiovascular disease is a leading cause of morbidity and mortality. In the past 3 decades, allostatic load-a physiological representation of cumulative life stress-has been associated with increased risk of cardiovascular disease incidence and mortality. Additionally, differences in allostatic load may partially explain persistent disparities in cardiovascular disease outcomes. However, there is notable variation in cardiovascular disease types and subsequent impairments suggesting this association may not be similar across cardiovascular disease types and demographic characteristics.
methodsThis study is a systematic review conducted in 2024 of current knowledge on the relationship between allostatic load and cardiovascular disease. A literature search using the electronic databases PubMed, SCOPUS, and Web of Science and the keywords allostatic load and cardiovascular disease was conducted. A total of 233 articles were identified in initial review and 22 studies were identified for inclusion in this review.
resultsThis review found that allostatic load was associated with a composite score of cardiovascular disease incidence but there was less clarity on the relationship with cardiovascular disease mortality and other cardiovascular disease outcomes. Additionally, there was some variation between cardiovascular disease types and the relationship with allostatic load as well as intersectional race and gender differences.
conclusionsThis review revealed notable gaps in the current knowledge of the relationship between cardiovascular disease and allostatic load. Future research is necessary to evaluate how this relationship differs across demographic characteristics, cardiovascular disease types, cardiovascular disease outcomes such as impairment, and disease processes. Future research should also identify standardized measures of allostatic load and determine how the social determinants impact allostatic load across the lifespan.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.