Evidence map›Paper›PMID 40054569›Full record

ArticleProgress in neuro-psychopharmacology & biological psychiatry2025

Noradrenergic modulation of stress induced catecholamine release: Opposing influence of FG7142 and yohimbine.

Vladimir Visocky, Carleigh J Turner, Matthew H Lowrie, Anthony Alibro, Fany Messanvi, Yogita Chudasama

Abstract read
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In one paragraph

Article in Progress in neuro-psychopharmacology & biological psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The anxiogenic drug yohimbine is a reinforcer in male and female rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Vladimir VisockySection on Behavioral Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: vladimir28.visocky@gmail.com.
Carleigh J TurnerSection on Behavioral Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.
Matthew H LowrieSection on Behavioral Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.
Anthony AlibroSection on Behavioral Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.
Fany MessanviSection on Behavioral Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.
Yogita ChudasamaSection on Behavioral Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: Yogita.chudasama@nih.gov.

Funding

Neural Circuits Underlying the Control of Executive and Emotional BehaviorZIAMH002951 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI CHUDASAMA, YOGITA · 2016 to 2025
$17.5M
Rodent Behavioral Core: The Analysis of BehaviorZICMH002952 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI CHUDASAMA, YOGITA · 2016 to 2025
$7.5M
Intramural NIH HHS ZIA MH002951Intramural NIH HHS ZIC MH002952
6 · The paper itself

Abstract

Life stress modulates decision making, particularly in the face of risk, in some cases prompting vulnerable populations to make suboptimal, life-altering choices. In the brain, stress is known to alter the extracellular release of catecholamines in structures such as basolateral amygdala (BLA) and nucleus accumbens (NAc), but the relationship between catecholamines and decision-making behavior under stress has not been systemically explored. We developed an operant touchscreen decision-making task for rats comprising elements of loss aversion and risk seeking behavior. Rats were first injected systemically with an adrenergic α

Indexed as

Adrenergic alpha-2 Receptor AntagonistsNorepinephrineStress, PsychologicalYohimbineAdrenergic alpha-2 Receptor AgonistsAnimalsBasolateral Nuclear ComplexCarbolinesConditioning, OperantDecision MakingDopamineGuanfacineMaleNucleus AccumbensRatsRats, Sprague-DawleyAdrenergic alpha-2 Receptor AgonistsAdrenergic alpha-2 Receptor AntagonistsCarbolinesDopamineFG 7142GuanfacineNorepinephrineYohimbineAmygdalaDecision-makingDopamineLoss aversionNucleus accumbensRisky behavior

Identifiers

PMID40054569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.