Evidence map›Paper›PMID 40053787›Full record

SynthesisJournal of medical Internet research2025

Effectiveness of AI for Enhancing Computed Tomography Image Quality and Radiation Protection in Radiology: Systematic Review and Meta-Analysis.

Subo Zhang, Zhitao Zhu, Zhenfei Yu, Haifeng Sun, Yi Sun, Hai Huang, Lei Xu, Jinxin Wan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Subo Zhang *Department of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0006-5038-5609
Zhitao Zhu *Department of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0005-7533-8748
Zhenfei YuDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0009-9677-8012
Haifeng SunDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0000-5578-4736
Yi SunDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0007-7467-2183
Hai HuangDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0001-2693-7024
Lei XuDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0005-8697-2779
Jinxin WanDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang, China.ORCID https://orcid.org/0009-0004-0407-5736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) presents a promising approach to balancing high image quality with reduced radiation exposure in computed tomography (CT) imaging.

objectiveThis meta-analysis evaluates the effectiveness of AI in enhancing CT image quality and lowering radiation doses.

methodsA thorough literature search was performed across several databases, including PubMed, Embase, Web of Science, Science Direct, and Cochrane Library, with the final update in 2024. We included studies that compared AI-based interventions to conventional CT techniques. The quality of these studies was assessed using the Newcastle-Ottawa Scale. Random effect models were used to pool results, and heterogeneity was measured using the I² statistic. Primary outcomes included image quality, CT dose index, and diagnostic accuracy.

resultsThis meta-analysis incorporated 5 clinical validation studies published between 2022 and 2024, totaling 929 participants. Results indicated that AI-based interventions significantly improved image quality (mean difference 0.70, 95% CI 0.43-0.96; P<.001) and showed a positive trend in reducing the CT dose index, though not statistically significant (mean difference 0.47, 95% CI -0.21 to 1.15; P=.18). AI also enhanced image analysis efficiency (odds ratio 1.57, 95% CI 1.08-2.27; P=.02) and demonstrated high accuracy and sensitivity in detecting intracranial aneurysms, with low-dose CT using AI reconstruction showing noninferiority for liver lesion detection.

conclusionsThe findings suggest that AI-based interventions can significantly enhance CT imaging practices by improving image quality and potentially reducing radiation doses, which may lead to better diagnostic accuracy and patient safety. However, these results should be interpreted with caution due to the limited number of studies and the variability in AI algorithms. Further research is needed to clarify AI's impact on radiation reduction and to establish clinical standards.

Indexed as

Artificial IntelligenceRadiation ProtectionTomography, X-Ray ComputedHumansRadiation Dosageartificial intelligencecomputed tomographyimage qualitymeta-analysisradiation protection

Identifiers

PMID40053787
PMCPMC11907168

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.