Evidence map›Paper›PMID 40053748›Full record

ArticleJournal of medical Internet research2025

Opportunities and Challenges in Using Electronic Health Record Systems to Study Postacute Sequelae of SARS-CoV-2 Infection: Insights From the NIH RECOVER Initiative.

Hannah L Mandel, Shruti N Shah, L Charles Bailey, Thomas Carton, Yu Chen, Shari Esquenazi-Karonika, Melissa Haendel, Mady Hornig, Rainu Kaushal, Carlos R Oliveira and 10 more

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Hannah L MandelDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0002-5685-9602
Shruti N ShahDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0002-0715-3187
L Charles BaileyApplied Clinical Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0002-8967-0662
Thomas CartonLouisiana Public Health Institute, New Orleans, LA, United States.ORCID https://orcid.org/0000-0003-0059-1990
Yu ChenDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0002-1519-4894
Shari Esquenazi-KaronikaDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0002-2040-0250
Melissa HaendelDepartment of Genetics, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0001-9114-8737
Mady HornigDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States.ORCID https://orcid.org/0000-0001-7572-3092
Rainu KaushalDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0002-4694-2517
Carlos R OliveiraDivision of Infectious Diseases, Department of Pediatrics, Yale University School of Medicine, New Haven, CT, United States.ORCID https://orcid.org/0000-0003-1897-6581
Alice A PerlowskiBlooming Magnolia, Los Angeles, CA, United States.ORCID https://orcid.org/0009-0000-4116-3875
Emily PfaffDepartment of Medicine, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0002-6840-9756
Suchitra RaoDepartment of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States.ORCID https://orcid.org/0000-0002-0334-6301
Hanieh RazzaghiApplied Clinical Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0001-5001-1590
Elle SeibertDepartment of Neuroscience, USC Dornsife College of Letters, Arts and Sciences, Los Angeles, CA, United States.ORCID https://orcid.org/0000-0001-6262-3965
Gelise L ThomasClinical and Translational Science Collaborative of Northern Ohio, Case Western Reserve University, Cleveland, OH, United States.ORCID https://orcid.org/0000-0002-7515-1642
Mark G WeinerDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0001-5586-9940
Lorna E ThorpeDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0002-5535-2674
Jasmin DiversDepartment of Foundations of Medicine, New York University Long Island School of Medicine, Mineola, NY, United States.ORCID https://orcid.org/0000-0003-0120-7620
RECOVER EHR CohortSee Acknowledgments, , .

Funding

OTA-21-015A Post-Acute Sequelae of SARS-CoV-2 Infection Initiative: NYU Langone Health Clinical Science Core, Data Resource Core, and PASC Biorepository CoreOT2HL161847 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GROSS, RACHEL SHARON, HORWITZ, LEORA · 2021 to 2025
$651.0M
Clinical Epidemiology of Pediatric COVID-19 and MIS-CK23AI159518 · NIAID · YALE UNIVERSITY · PI OLIVEIRA, CARLOS RAFAEL · 2021 to 2024
$729k
NHLBI NIH HHS OT2 HL161847NIAID NIH HHS K23 AI159518
6 · The paper itself

Abstract

The benefits and challenges of electronic health records (EHRs) as data sources for clinical and epidemiologic research have been well described. However, several factors are important to consider when using EHR data to study novel, emerging, and multifaceted conditions such as postacute sequelae of SARS-CoV-2 infection or long COVID. In this article, we present opportunities and challenges of using EHR data to improve our understanding of long COVID, based on lessons learned from the National Institutes of Health (NIH)-funded RECOVER (REsearching COVID to Enhance Recovery) Initiative, and suggest steps to maximize the usefulness of EHR data when performing long COVID research.

Indexed as

COVID-19Electronic Health RecordsHumansNational Institutes of Health (U.S.)Post-Acute COVID-19 SyndromeSARS-CoV-2United Statesclinical data research networkclinical research networkcommon data modelCOVID-19digital healthelectronic health record dataelectronic health record networkelectronic health recordselectronic medical recordepidemiologicalinfectioninfectiousLong COVID, post-acute COVID-19 syndromemachine learningmedical informaticspandemicpost-infection syndromepublic health surveillancerespiratorySARS-CoV-2

Identifiers

PMID40053748
PMCPMC11923460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.