Evidence map›Paper›PMID 40053619›Full record

ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2025

Human-in-the-Loop Myoelectric Pattern Recognition Control of an Arm-Support Robot to Improve Reaching in Stroke Survivors.

Joseph V Kopke, Michael D Ellis, Levi J Hargrove

Abstract read
In one paragraph

Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph V Kopke
Michael D Ellis
Levi J Hargrove

Funding

Progressive Abduction Loading Therapy: A Phase IIb Stroke Rehabilitation Trial with Longitudinal TrackingR01HD096071 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ELLIS, MICHAEL D. · 2019 to 2023
$2.6M
NICHD NIH HHS R01 HD096071
6 · The paper itself

Abstract

The objective of this study was to assess the feasibility and efficacy of using real-time human-in-the-loop pattern recognition-based myoelectric control to control vertical support force or vertical position to improve reach in individuals with chronic stroke. This work attempts to move proven lab-based static arm support paradigms towards a controllable wearable device. A machine learning (linear discriminant analysis)-based myoelectric pattern recognition system based on movement intent as determined by real-time muscle activation was used to control incremental changes in either vertical position or vertical support force during a reach and retrieve task, with the goal of improving reaching function. Performance under real-time control of both options was compared to two unchanging static-support conditions (current gold standard) and a no-support condition. Both real-time control paradigms were successfully implemented and resulted in greater forward-reaching performance as demonstrated by increased elbow extension and horizontal shoulder adduction compared to no-support and was not different from the current gold standard static support paradigms. Muscle activation levels with real-time support were lower than the no-support condition and similar to those observed during the static support paradigms. Real-time detection of user intent was successful in controlling both vertical position and vertical support force and enabled greater reaching distance than without it demonstrating both its feasibility and efficacy albeit with some limitations.

Indexed as

ArmElectromyographyPattern Recognition, AutomatedRoboticsStroke RehabilitationAdultAgedAlgorithmsBiomechanical PhenomenaDiscriminant AnalysisFeasibility StudiesFemaleHumansMachine LearningMaleMiddle Aged

Identifiers

PMID40053619
PMCPMC12013382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.