Evidence map›Paper›PMID 40053578›Full record

ArticleScience advances2025

Perirhinal cortex abnormalities impair hippocampal plasticity and learning in

Rachel E Keith, Yiming Shen, Jordan A Janzen-Meza, Joseph Abramovitz, Priscila C Antonello, Aysha Hameed, Baskar Mohana Krishnan, Michelle W Antoine

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rachel E KeithSection on Neural Circuits, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.ORCID 0009-0007-1253-0171
Yiming ShenSection on Neural Circuits, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-8404-3136
Jordan A Janzen-MezaWashington University School of Medicine, St. Louis, MO, USA.ORCID 0009-0003-5105-093X
Joseph AbramovitzSection on Neural Circuits, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.ORCID 0009-0003-5393-5870
Priscila C AntonelloSection on Neural Circuits, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-0624-1169
Aysha HameedGeorge Mason University, Fairfax, VA, USA.ORCID 0009-0001-3380-9362
Baskar Mohana KrishnanSection on Neural Circuits, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Michelle W AntoineSection on Neural Circuits, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-7222-7309

Funding

Neuroscience Training Program at Washington UniversityT32NS121881 · NINDS · WASHINGTON UNIVERSITY · PI Martha W Bagnall, Daniel Kerschensteiner · 2021 to 2026
$3.1M
NINDS NIH HHS T32 NS121881
6 · The paper itself

Abstract

Learning and memory deficits, including spatial navigation difficulties, are common in autism spectrum disorder (ASD). Several ASD mouse models (

Indexed as

Autistic DisorderFragile X Messenger Ribonucleoprotein 1HippocampusLearningNAV1.2 Voltage-Gated Sodium ChannelNeuronal PlasticityProtein Serine-Threonine KinasesAnimalsDisease Models, AnimalLong-Term PotentiationMaleMiceMice, KnockoutSpatial LearningCDKL5 protein, mouseFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1NAV1.2 Voltage-Gated Sodium ChannelProtein Serine-Threonine Kinases

Identifiers

PMID40053578
PMCPMC11887805

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.