Evidence map›Paper›PMID 40053263›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2025

Antidiabetic and Antioxidant Molecules of Ficus tikoua and their Combined Effect: Bioassay-Guided Isolation, In Vitro and In Silico Analysis.

Hanlei Wang, Jing Lu, Xuelin Chen, Kun Zhang, Xia Zhao, Yumei Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanlei Wang *Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Jing Lu *Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Xuelin ChenXishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Kun ZhangXishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Xia ZhaoXishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China.
Yumei ZhangXishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, 650223, China. zymei@xtbg.ac.cn.

Funding

The Special Project for Environmental Protection in Yunnan Province E1YN051KYunnan Revitalization Talents Support Plan XDYC-CYCX-2022-0052
6 · The paper itself

Abstract

Ficus tikoua has high medicinal and edible value. Our previous study had demonstrated its antidiabetic properties, but the specific active molecules and their mechanisms remained unclear. In this study, five active compounds, namely marmesin glycoside (1), quercetin (2), quercetin 3-O-β-D-glucuronide-6''-methyl ester (3), (-)-epicatechin (4), (+)-epicatechin (5), were isolated by bioassay-guided method and identified. Compounds 1-5 displayed varying degrees of efficacy (IC

Indexed as

AntioxidantsFicusHypoglycemic AgentsPlant Extracts3T3-L1 Cellsalpha-GlucosidasesAnimalsBiological AssayCatechinComputer SimulationGlucoseGlycoside Hydrolase InhibitorsMiceQuercetinalpha-GlucosidasesAntioxidantsCatechinGlucoseGlycoside Hydrolase InhibitorsHypoglycemic AgentsPlant ExtractsQuercetin3T3-L1 adipocytesDNA protective effectFicus tikouaMolecular dynamicsSynergistic effectα-Glucosidase

Identifiers

PMID40053263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.