Evidence map›Paper›PMID 40052898›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Ion-Pair Hydrogen Atom Transfer Catalysis Enables Cr-Catalyzed Allylation of Ketones Using Hydrocarbon Alkenes.

Suguru Arii, Zonghan Yu, Hongyu Chen, Harunobu Mitsunuma, Motomu Kanai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suguru AriiGraduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Zonghan YuGraduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Hongyu ChenGraduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Harunobu MitsunumaGraduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Motomu KanaiGraduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Funding

JSPS KAKENHI JP20H05843JSPS KAKENHI JP23H04909JSPS KAKENHI JP23K06045
6 · The paper itself

Abstract

We report a catalytic allylation of ketones using simple hydrocarbon alkenes, enabled by a synergistic system comprising chromocene and photo-activatable ion-pair hydrogen atom transfer (IP-HAT) catalysts derived from a thiophosphoryl imide and N-heteroaromatics. This catalyst system generates highly nucleophilic, electron-rich allylchromium(III) species directly from unactivated alkenes, demonstrating broad applicability to various ketones, including aromatic, aliphatic, and multifunctional ketones. The reaction proceeds under mild conditions with high functional group tolerance. The modular design of the IP-HAT catalysts allows precise tuning of redox potential and HAT activity, with the enhanced reduction potential of the reduced N-heteroaromatics catalyst playing a pivotal role in efficiently regenerating the electron-rich chromocene(II) catalyst.

Indexed as

AllylationChromiumHydrocarbon alkeneIon pairKetone

Identifiers

PMID40052898
PMCPMC12087839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.