Evidence map›Paper›PMID 40052732›Full record

ArticleThe journal of physical chemistry. B2025

Thermodynamic Parameter Estimation for Modified Oligonucleotides Using Molecular Dynamics Simulations.

Soon Woo Park, Junehawk Lee, Jung Woo Park, Moon Ki Kim, Sangjae Seo

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Soon Woo ParkCenter for Nanotubes and Nanostructured Composites, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Junehawk LeeCenter for Biomedical Computing, Division of National Supercomputing, Korea Institute of Science and Technology Information, Daejeon 34141, Republic of Korea.
Jung Woo ParkCenter for Biomedical Computing, Division of National Supercomputing, Korea Institute of Science and Technology Information, Daejeon 34141, Republic of Korea.
Moon Ki KimCenter for Nanotubes and Nanostructured Composites, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0003-0819-5909
Sangjae SeoDepartment of High-Fidelity Model Acceleration Research, Division of National Supercomputing, Korea Institute of Science and Technology Information, Daejeon 34141, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the thermodynamic parameters of 1300 RNA/DNA hybrid duplexes, including both natural and chemically modified forms, using molecular dynamics (MD) simulations. Modified duplexes consist of phosphorothioate (PS) backbones and 2'-

Indexed as

Molecular Dynamics SimulationOligonucleotidesThermodynamicsDNANucleic Acid ConformationRNADNAOligonucleotidesRNA

Identifiers

PMID40052732
PMCPMC11932115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.