Evidence map›Paper›PMID 40052648›Full record

ArticleJournal of cosmetic dermatology2025

Concomitant Use of Botulinum Toxin and Super Long Nd:YAG Laser.

Jernej Kukovič, Anže Zorman

Abstract readCase Reports
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jernej KukovičMedilase d.o.o, Ljubljana, Slovenia.
Anže ZormanMedilase d.o.o, Ljubljana, Slovenia.ORCID https://orcid.org/0000-0003-3777-6497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBotulinum toxin is a widely utilized minimally invasive therapeutic option with minimal downtime and a low risk of serious complications. The long pulse Nd:YAG laser treatment (PIANO) has been utilized in recent years for skin rejuvenation and tightening, body shaping, and transdermal lipolysis through bulk heating of the tissue. The heat-labile bond between the heavy and light chains of botulinum toxin could be affected by laser bulk heating.

aimsThis case series aims to clinically evaluate the efficacy of botulinum toxin when used in conjunction with PIANO 1064 nm bulk heating. PATIENTS/

methodsThis case series included two patients who underwent standard hyperhidrosis treatment with botulinum toxin and then single-sided concomitant long-pulsed Nd:YAG laser treatment.

resultsThe iodine-starch test revealed no differences between the two areas at follow-up visits.

conclusionThis small study corroborates the findings of other research indicating that long-pulsed 1064 nm Nd:YAG laser treatment does not affect the efficacy of botulinum toxin.

Indexed as

Botulinum Toxins, Type ACosmetic TechniquesHyperhidrosisLasers, Solid-StateLow-Level Light TherapyCombined Modality TherapyHumansRejuvenationTreatment OutcomeBotulinum Toxins, Type Abotulinum toxinNd:YAG laserPIANO

Identifiers

PMID40052648
PMCPMC11887420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.