Evidence map›Paper›PMID 40052555›Full record

ArticleMolecular medicine reports2025

Investigating the molecular mechanism of purslane‑based vitiligo treatment using network pharmacology, molecular docking and

Xueying Zhang, Lele Meng, Xiaorong Ran, Shuang Li, Changhui Wen

Abstract read
In one paragraph

Article in Molecular medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xueying ZhangThe First Clinical College, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, P.R. China.
Lele MengThe First Clinical College, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, P.R. China.
Xiaorong RanThe First Clinical College, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, P.R. China.
Shuang LiThe First Clinical College, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, P.R. China.
Changhui WenDepartment of Dermatology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550001, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purslane is a traditional Chinese medicine with a long‑standing history of efficacy in the management of dermatological conditions such as vitiligo. However, the molecular mechanisms underlying its therapeutic effects on vitiligo remain unclear. Therefore, the present study explored these mechanisms using network pharmacology, molecular docking and

Indexed as

Drugs, Chinese HerbalNetwork PharmacologyVitiligoCell SurvivalHumansMolecular Docking SimulationOxidative StressPPAR gammaProto-Oncogene Proteins c-aktSignal TransductionDrugs, Chinese HerbalPPAR gammaProto-Oncogene Proteins c-aktoxidative stressPI3K/AKT pathwaypurslanepurslane total flavonesreactive oxygen speciesvitiligo

Identifiers

PMID40052555
PMCPMC11905198

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.