ArticleClinical and experimental dental research2025
The Use of Cyanoacrylate Tissue Adhesives in Various Wound Suturing Techniques to Enhance the Healing Process of Surgical Wounds: An Animal Study.
Article in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Impact of α-cyanoacrylate tissue adhesive on soft tissue healing at donor sites in free gingival graft surgery: a randomized controlled clinical trial.Head & face medicine · 2026Trial
- Use of UV-Polymerizable Methacrylate Adhesive as a Post-Recovery Bandage Replacement for Transphyseal Screw Incisions in Horses: A Pilot Study.Animals : an open access journal from MDPI · 2026Article
- Cyanoacrylate Tissue Adhesives in Peri-Implant Surgery: A Case Report and Surgical Technique.Clinical case reports · 2025Article
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Authors and funding
5 authors.
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Abstract
objectivesThis study aimed to investigate the effect of cyanoacrylate tissue adhesive and suture techniques on closing surgical wounds in rabbits. MATERIALS AND
methodsThis study randomly divided 32 male New Zealand white rabbits into four groups. In the first group, interrupted sutures were applied. In the second group, interrupted sutures were placed, and using a pipette, the surface of the wound was covered by tissue adhesive. In the third group, the wound was closed with a continuous suture, and in the fourth group, in addition to the continuous suture, tissue adhesive was also used. On the fifth day of surgery, rabbits were killed and tissue samples were collected and examined for epithelial tissue thickness, rate of inflammatory tissue, and area of granulation tissue.
resultsIn general, among the four groups, the highest thickness of the formed epithelial tissue was in the continuous suture without tissue adhesive group, and the lowest of epithelial tissue was seen in the interrupted suture with tissue adhesive group. There was a tendency to reduce the intensity of inflammation in the groups that used tissue adhesive, but except in one case, no significant difference was seen in the rest of the groups. Among the studied groups, the rate of granulation tissue was less in the continuous suture with an adhesive group compared with the other groups.
conclusionsThe use of tissue adhesive on any type of suture technique can reduce the rate of inflammation and cause less granulation tissue. In the short term, the use of tissue adhesive could be an obstacle in the formation of epithelial tissue.
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