ArticleHistology and histopathology2025
Chelerythrine-mediated targeting of NF-κB and Nrf2 pathways alleviates liver injury in a carbon tetrachloride-induced liver fibrosis mouse model.
Article in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The trial behind it
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Who cites it
4 citing papers in PubMed.
- The Effects of Drugs on CYP3A Enzyme Activity and Protein Expression Through Ubiquitination Modification Regulation.Basic & clinical pharmacology & toxicology · 2025Article
- Chelerythrine Protects Against Acetaminophen-Induced Acute Liver Injury: Insights from Gut Microbiota and Multi-Omics Analysis.Antioxidants (Basel, Switzerland) · 2025Article
- Integration bile acid metabolomics and gut microbiome to study the anti-liver fibrosis effects of total alkaloids of Corydalis saxicola Bunting.Chinese medicine · 2025Article
- Development and preliminary mechanistic analysis of compound effervescent hepatoprotective granules.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BACKGROUND AND
aimsThis study aimed to investigate the mechanism and efficacy of chelerythrine (CHE) in treating carbon tetrachloride (CCl
methodsMice were induced with CCl
resultsThe findings demonstrated that CHE significantly ameliorated oxidative damage, inflammatory response, and liver fibrosis in CCl
conclusionsThese results suggest that CHE can alleviate liver fibrosis in CCl
Indexed as
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Registered trials
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