Evidence map›Paper›PMID 40052179›Full record

ArticleOrthopaedic journal of sports medicine2025

Evaluation of the Stability, Revision Rate, and Complication Profile of Combined Anterior Cruciate Ligament Reconstruction with Lateral Extra-Articular Tenodesis and Hughston Procedure in Anterior Cruciate Ligament and Medial Collateral Ligament Injury: An 8-Year Cohort Study.

Gian Andrea Lucidi, Emanuele Altovino, Stefano Di Paolo, Piero Agostinone, Francesca Maria Marziano, Nicola Pizza, Giacomo Dal Fabbro, Alberto Grassi, Stefano Zaffagnini

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gian Andrea LucidiClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.
Emanuele AltovinoClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.
Stefano Di PaoloClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.ORCID https://orcid.org/0000-0002-1761-7352
Piero AgostinoneClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.
Francesca Maria MarzianoClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.
Nicola PizzaClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.
Giacomo Dal FabbroClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.
Alberto GrassiClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.
Stefano ZaffagniniClinica II, IRCCS, Istituto Ortopedico Rizzoli, Via Pupilli, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anterior cruciate ligament (ACL) tears combined with medial collateral ligament (MCL) injury has been associated with an increased rate of ACL reconstruction (ACLR) failure, high-grade pivot shift (PS), and lower return to sports rate. On the other hand, medial-sided procedures in the setting of ACLR are associated with knee stiffness and arthrofibrosis. Purpose/Hypothesis: This study aimed to compare clinical scores, objective knee laxity, failure, and complication rates in 2 different patient groups. The combination of ACL reconstruction with LET and the Hughston procedure yields comparable failure rates, complication rates, and clinical outcomes to ACL reconstruction with LET in patients without medial instability. Study Design: Cohort study; Level of evidence, 3. Methods: A group of patients had a combined ACL and MCL injury grade 2 with chronic instability and underwent ACLR associated with lateral extra-articular tenodesis (LET) and the Hughston procedure (Hughston group). The control group included matched patients with isolated ACL lesion without medial instability who underwent ACL reconstruction with LET (control group). Patient-reported outcome measures, complications, and reoperations were collected for both groups. A clinical evaluation was performed including objective anteroposterior laxity measurement (KT-1000 arthrometer) and PS quantification. The primary outcomes were ACL revision and ACL-clinical failure, a composite parameter of anteroposterior and rotatory laxity. A test for 2-way analysis of variance for repeated measures was performed to assess the between-group differences ( Results: A total of 70 patients (35 per group) were enrolled in the present study at a follow-up of 8.1 ± 2.7 years. All the patient-reported outcome measures significantly improved at the final follow-up with no difference between the 2 groups ( Conclusion: Due to its simplicity and cost-effectiveness, the Hughston technique should be included in the orthopaedic surgeon's armamentarium for the treatment of moderate anteromedial instability in combined ACL and MCL injury. Moreover, the outcomes and failure rate of the Hughston technique combined with an ACLR + LET are similar to that of an ACLR + LET used to treat an isolated ACL injury.

Indexed as

ACLanterolateral instabilityanteromedial instabilitykneeligamentMCLpivot shift

Identifiers

PMID40052179
PMCPMC11881936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.