Evidence map›Paper›PMID 40052164›Full record

ArticleClinical kidney journal2025

COVID-19 among kidney transplant recipients: evaluating risk factors during the initial phase of the pandemic.

Alexandra Nowak, Aurora Caldinelli, Mårten Segelmark, Helena Rydell, Angelica Artborg, Rino Bellocco, Maria Stendahl, Bengt Lindholm, Julia Wijkström, Marie Evans

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra NowakDivision of Renal Medicine, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7157-9644
Aurora CaldinelliDivision of Renal Medicine, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Mårten SegelmarkDepartment of Clinical Sciences, Division of Nephrology, Lund University and Department of Endocrinology, Nephrology and Rheumatology, Skane University Hospital Lund, Sweden.ORCID https://orcid.org/0000-0002-1221-0772
Helena RydellDivision of Renal Medicine, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Angelica ArtborgDivision of Renal Medicine, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Rino BelloccoUniversity of Milano-Bicocca, Department of Biostatistics, Milano, Italy.
Maria StendahlDepartment of Internal Medicine, Ryhov Hospital Jönköping, Sweden.
Bengt LindholmDivision of Renal Medicine, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Julia WijkströmDivision of Renal Medicine, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-6183-5878
Marie EvansDivision of Renal Medicine, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-8650-5795

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current knowledge about risk factors for severe COVID-19 among kidney transplant recipients stem from meta-analyses of small or regional studies. Methods: All kidney transplant recipients in Sweden as of 1 January 2020 ( Results: Male sex increased the risk of severe COVID-19. While many comorbidities were associated with increased risk, their significance diminished after adjustment for other factors. Kidney transplant recipients of working age, 49-58 years adjusted odds ratio (aOR) 2.32 (95% CI 1.53-3.51) and 59-68 years aOR (1.92; 1.26-2.91) had the highest risk compared to the youngest age group (18-38 years). Compared to recently (<1 year) transplanted patients, those transplanted >5 years ago had a lower risk of severe COVID-19 (aOR 0.52; 0.36-0.75 for 6-10 years; aOR 0.57; 0.41-0.79 for >10 years). Longer pre-transplant dialysis vintage (aOR Conclusions: While kidney transplant recipients share risk factors with the general population, working age groups were at the highest risk, unlike in the general population. These findings emphasize the need for targeted prevention and treatment strategies for kidney transplant recipients in future pandemics.

Indexed as

COVID-19epidemiologykidney transplantationproton pump inhibitorworking age

Identifiers

PMID40052164
PMCPMC11883224

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.