ArticleJournal of pain research2025
Genicular Nerve Radiofrequency Ablation for Chronic Knee Joint Pain Using a V-Shaped Active Tip Needle: A Single-Center Retrospective Observational Study.
Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genicular Nerve Radiofrequency Ablation for Persistent Postsurgical Pain After Total Knee Arthroplasty: A Systematic Review of Clinical Effectiveness and Safety.BioMed research international · 2026Pooled it
- Lateral Femoral Cutaneous Nerve Radiofrequency Ablation for the Treatment of Meralgia Paresthetica: A Retrospective Case Series.Advances in therapy · 2026Article
- Ultrasound-Guided Genicular Nerve Block: Novel Clinical Role for Postoperative Knee Replacement Surgery Pain Management.Current pain and headache reports · 2026Review
- Percutaneous denervation for the treatment of knee pain.Skeletal radiology · 2026Review
- Interventional Pain Procedures: A Narrative Review Focusing on Safety and Complications. Part 4 - Peripheral Nerve, Joint, Musculoskeletal, and Regenerative Interventions.Journal of pain research · 2026Review
- Interventional Pain Procedures: A Narrative Review Focusing on Safety and Complications. Part 3 - Sympathetic and Ganglion-Targeted Techniques.Journal of pain research · 2026Review
- Genicular Nerve Ultrasound-Guided Cryoanalgesia for the Treatment of Chronic Knee Joint Pain: An Observational Retrospective Study.Pain and therapy · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic knee pain from osteoarthritis (OA) affects a significant proportion of adults over 40. Total knee arthroplasty (TKA) remains the standard for advanced OA, yet up to 20% of patients experience chronic postsurgical pain (CPSP). Genicular nerve radiofrequency ablation (GNRFA) can alleviate pain in those unresponsive to conservative treatments or TKA. However, anatomical variability of the genicular nerves may limit treatment durability. This retrospective, single-center observational study investigated whether using a novel V-shaped active tip needle-which creates larger lesions-could improve outcomes. Methods: Fifty patients with symptomatic knee OA or CPSP, who had a ≥50% reduction in pain after diagnostic genicular nerve blocks, underwent GNRFA with a V-shaped active tip needle between September 2020 and January 2022. Pain and function were assessed using the visual analogue scale (VAS) at rest and during movement, Western Ontario and McMaster Universities Arthritis Index (WOMAC), Douleur Neuropathique en 4 Questions (DN4), and EuroQol-5 Dimensions (EQ-5D) at baseline and 1, 3, 6, and 9 months post-procedure. Results: By 6 months, 64% of patients showed ≥50% reduction in VAS pain scores, sustained at 9 months (p<0.0001). Median WOMAC scores improved from 62.0 at baseline to 40.0 at 6 months (p<0.0001). DN4 scores declined from a median of 4.0 at baseline to 2.0 at 6 months and 1.0 at 9 months (p<0.001). EQ-5D scores demonstrated significant enhancement in quality of life (p<0.01). Pain intensity differences at rest and during movement remained substantially improved at 9 months (p<0.0001). Conclusion: GNRFA using a V-shaped active tip needle is a promising intervention for chronic knee pain, offering significant and sustained pain relief and functional improvement. Larger lesions created by the novel needle may overcome anatomical challenges, though further randomized studies are warranted to validate efficacy and safety.
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