Evidence map›Paper›PMID 40052123›Full record

ArticleFrontiers in oncology2025

Validation of an albumin-indocyanine green-based China liver cancer staging system to evaluating resectable hepatocellular carcinoma patients and comparison with the Child-Pugh-based China liver cancer staging system.

MinQiang Chen, Chao Ren, MengXia Wang, Min Yu, Bo Wu, Bo Zhuang, JianXiang Jin, YaoQi Zhang, ShiAn Yu

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

MinQiang Chen *Department of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
Chao Ren *Department of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
MengXia WangDepartment of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
Min YuDepartment of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
Bo WuDepartment of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
Bo ZhuangDepartment of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
JianXiang JinDepartment of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
YaoQi ZhangDepartment of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.
ShiAn YuDepartment of Hepatobiliary and Pancreatic Surgery, Jinhua Municipal Central Hospital Medical Group, Jinhua, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Here, the utility of an albumin-indocyanine green-based China liver cancer (CNLC) staging system (ALICE-CNLC) as a tool for the prognostic assessment of hepatocellular carcinoma (HCC) patients was evaluated, comparing this system to the Child-Pugh score-based CNLC staging system. Methods: The cohort for this study included 331 patients with HCC who had undergone hepatectomy at Jinhua Municipal Central Hospital Medical Group in China from April 2012-June 2021 and had postoperative pathology-confirmed HCC. Kaplan-Meier survival curves were generated, with log-rank tests used to examine prognostic factors. Univariate and multivariate analyses were used for identification of outcome predictors using Cox proportional hazards regression. Results: The prediction of overall survival (OS) by the ALICE-CNLC system for patients with stage Ia disease was markedly better than that for patients with stage Ib and IIa disease ( Conclusion: The ALICE-CNLC and CNLC staging systems did not show significant differences in predicting the prognosis of patients with HCC who have undergone hepatectomy.

Indexed as

albumin-indocyanine greenchina liver cancer staginghepatocellular carcinomaoverall survivalprognostic impactrecurrence-free survival

Identifiers

PMID40052123
PMCPMC11882571

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.