ReviewFrontiers in veterinary science2025
Neuroanatomy of spinal nociception and pain in dogs and cats: a practical review for the veterinary clinician.
Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Molecular and Immunohistochemical Analyses of PLIN4 in the Spinal Cord and Brain During the Development of Electroacupuncture-Induced Analgesic Tolerance in Mice.Veterinary medicine and science · 2026Article
- Assessment of pharmacokinetic parameters, oral bioavailability, and physiological effects of amantadine in horses.BMC veterinary research · 2026Article
- Cervical Pain in Non-Chondrodystrophic Dogs: Associations with Clinical Onset, Neurological Group and Disease Category.Animals : an open access journal from MDPI · 2026Article
- Impact of combined unilateral mastectomy and ovariohysterectomy on acute phase response and wound healing in dogs with mammary gland tumors.BMC veterinary research · 2026Article
- Amantadine as a therapeutic option for neuropathic pain in dogs with degenerative lumbosacral stenosis.BMC veterinary research · 2025Article
- Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic pain is a prevalent condition in companion animals and poses significant welfare challenges. To address these concerns effectively, veterinary clinicians must have a comprehensive understanding of the neuroanatomy of nociception and the intricate processes underlying pain perception. This knowledge is essential for planning and implementing targeted treatment strategies. However, much of the existing information on pain mechanisms is derived from studies on rodents or humans, highlighting the need for further translational research to bridge this gap for veterinary applications. This review aims to provide veterinary clinicians with an in-depth overview of the spinal nociceptive pathways in the dog and cat, tracing the journey from nociceptor activation to cortical processing in the brain. Additionally, the review explores factors influencing nociceptive signaling and pain perception. By enhancing the understanding of these fundamental physiological processes, this work seeks to lay the groundwork for developing effective therapies to manage the complexities of chronic pain in companion animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.