Evidence map›Paper›PMID 40051929›Full record

ArticleCureus2025

Salvage Surgery for Epidermal Growth Factor Receptor-Mutant Lung Cancer With Osimertinib Resistance: A Case Report.

Shinya Otsuka, Yutaro Nagano, Makoto Shioya, Hiroya Ohkawa, Tatsuya Kato

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shinya OtsukaDepartment of Thoracic Surgery, Hokkaido University Hospital, Sapporo, JPN.
Yutaro NaganoDepartment of Respiratory Medicine, Otaru General Hospital, Otaru, JPN.
Makoto ShioyaDepartment of Respiratory Medicine, Otaru General Hospital, Otaru, JPN.
Hiroya OhkawaDepartment of Surgical Pathology, Hokkaido University Hospital, Sapporo, JPN.
Tatsuya KatoDapartment of Thoracic Sugery, Hokkaido University, Sapporo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advancements in lung cancer treatment, including molecular targeted therapies and immune checkpoint inhibitors, have significantly improved patient outcomes and extended survival. However, the efficacy and safety of salvage surgery for lesions resistant to targeted therapy like osimertinib remain poorly understood. This report highlights a case of salvage surgery performed on a patient with epidermal growth factor receptor (

Indexed as

drug resistanceegfr t790m mutationlung cancermolecular targeted therapiesosimertinibsalvage surgery

Identifiers

PMID40051929
PMCPMC11883140

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.