ReviewFrontiers in plant science2025
Spray-induced gene silencing for crop protection: recent advances and emerging trends.
Review in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Cross-kingdom RNA in plant-microbe interactions: from molecular interactions to next-generation crop protection.Stress biology · 2026Review
- Environmental Risk Assessment and Confinement of Genetically Engineered Trees with an Emphasis on Vegetative Reproduction.Plants (Basel, Switzerland) · 2026Review
- Nano-enabled spray-induced RNA interference against fungal pathogens of oilseed crops: carrier performance, delivery evidence and field translation.World journal of microbiology & biotechnology · 2026Review
- Envisaging the role of plant Small RNAs: A comprehensive review on antiviral defense mechanisms.Molecular biology reports · 2026Review
- Rational dsRNA design, scalable production and nanodelivery to enhance spray-induced gene silencing.Communications biology · 2026Review
- Calcium Alginate-Based Hydrogel-Encapsulated Nutrients and Nucleic Acid Delivery for Ameliorating Saline-Alkali Stress in Plants.Gels (Basel, Switzerland) · 2026Review
- Enhancing Fusarium resistance in Nigella sativa via spray-induced gene silencing (SIGS) using chitosan nanoparticles with molecular and phytochemical perspectives.Scientific reports · 2026Article
- Extending bananas shelf life by dsRNA mediated interference of ethylene synthesis.Food chemistry. Molecular sciences · 2026Article
- LUCID: An Integrative Approach for Target Discovery and dsRNA Design in Plant Fungal Pathogens.Plant biotechnology journal · 2026Article
- The unfulfilled potential of nanocarriers for RNA delivery in antiviral crop protection.Nature plants · 2026Review
- Sprayable dsRNA for integrated crop defense: mechanisms, delivery strategies, and translational challenges.Molecular biology reports · 2026Review
- Molecular Mechanisms and Metabolic Responses in the Biological Antagonism BetweenMicroorganisms · 2026Article
- Biogenic Fe₂O₃ nanoparticles enhance carotenoid pathway gene expression and suppress verticillium root rot in marigold (Tagetes erecta).BMC plant biology · 2026Article
- Advances in the Control of Plant Fungal Pathogens.Journal of fungi (Basel, Switzerland) · 2026Review
- Exploiting plant immune "switches" for resistance engineering.Stress biology · 2026Review
- Domain-Targeted RNAi of VeA Reveals Its Essential Role in the Fusarium oxysporum-Pseudostellaria heterophylla Interaction.Molecular plant pathology · 2026Article
- Enhancing apple disease resistance via magnetic nanoparticle-mediated delivery of artificial miRNAs that suppress a tRNA-derived small RNA targeting a disease-resistant gene.Plant communications · 2026Article
- Comparative efficacy of conventional and nano-formulations of silica and chitosan against Fusarium oxysporum causing wilt in pea (Pisum sativum).BMC plant biology · 2026Article
- Molecular pathways in plant growth-promoting rhizobacteria-plant interactions: a comprehensive review.Archives of microbiology · 2026Review
- Molecular Identification and RNA-Based Management of Fungal Plant Pathogens: From PCR to CRISPR/Cas9.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The RNA-based spray-induced gene silencing (SIGS) technology represents an ecologically sustainable approach to crop protection and pathogen management. Following the recent approval of Ledprona as the first sprayable double-stranded RNA (dsRNA) biopesticide by the EPA at the end of 2023, SIGS has emerged as a focal point in both academic and industrial sectors. This review analyzes recent advances and emerging trends in SIGS. The application of SIGS for crop protection, including the control of insects, fungal pathogens, and viruses, is briefly summarized. Distinguishing this review from others, we delve into practical aspects of the technology, such as the selection and screening of target genes, large-scale production methods, and delivery systems, highlighting major advancements in these areas and also addressing the remaining questions and issues, particularly concerning safety concerns and controlling harmful weeds. Finally, this review emphasizes the emerging trends in SIGS technology, particularly its integration with nanotechnology and other methodologies. Collectively, the rapid progress in SIGS studies is poised to accelerate the maturation and application of this technology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.