ArticleJournal of surgical case reports2025
Dedifferentiated liposarcoma of transverse colon: a case report and review of the literature.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Dedifferentiated liposarcoma (DDL) is an aggressive subtype of liposarcoma that rarely arises within the abdominal cavity. We describe the case of a 71-year-old female incidental transverse colon mass suspicious for colorectal cancer. Pre-operative biopsy at colonoscopy was not possible due to the lesion's extraluminal location; however, complete resection was achieved through left hemicolectomy. Histology confirmed DDL. Review of the literature found four additional cases of DDL in the transverse colon. Clinical presentation, management, and follow-up were reviewed, illustrating poor outcomes; three of the five cases died within 3 years of surgery. DDL is associated with higher rates of local recurrence, metastasis, and mortality compared to well-differentiated liposarcomas. While limited by its rarity, DDL in the transverse colon appears to follow similarly poor outcomes.
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