ArticleEuropean journal of case reports in internal medicine2025
Aggressively Quick: A Case of Negative Radiographic Evidence Progressing to a Large Lobulated Lung Mass In Six Months.
Article in European journal of case reports in internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We present the case of a 61-year-old male with a past medical history of diabetes, hypertension, obstructive sleep apnea, obesity hypoventilation syndrome, and chronic obstructive pulmonary disease (COPD), who developed a rapidly growing lung mass after previously having no radiographic evidence of cancer 6 months earlier. The patient initially presented for what appeared to be a COPD exacerbation, and imaging at that time showed no sign of any lung mass. Six months later, the patient returned with dyspnea and was found to have a large lobulated lung mass, possibly extending into the mediastinum. Lung malignancies include small cell carcinomas and non-small cell carcinomas. In this case, the patient developed an indeterminate differentiation of a non-small cell carcinoma, which rapidly progressed from negative radiographic findings to a 9.7 cm mass at its largest dimension within 6 months. LEARNING POINTS: Recognize the significance of highly proliferative lung cancer with volume doubling time metric.Review and understand lung cancer screening, tumor differentiation, and prognostic factors.
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