ArticlePsychedelic medicine (New Rochelle, N.Y.)2024
Perceived Risk of Trying Lysergic Acid Diethylamide in the United States from 2015 to 2019: Are Americans Assessing Lysergic Acid Diethylamide's Risk Profile More Favorably?
Article in Psychedelic medicine (New Rochelle, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Who Keeps Using Lysergic Acid Diethylamide? Correlates of Past-Year Use in People Who Initiated Use at least Five Years Ago.Psychedelic medicine (New Rochelle, N.Y.) · 2026Article
- Association Between Lifetime Hallucinogen Use and Valvular Heart Disease: Findings from the All of Us Research Program.Journal of psychoactive drugs · 2026Article
- Perceived Availability of Lysergic Acid Diethylamide in the United States from 2015 to 2019.Psychedelic medicine (New Rochelle, N.Y.) · 2026Article
- Review
- Do undergraduates' views of psychedelics relate to the context for psychedelic use?Drug science, policy and law · 2025Article
- Ensuring Access to Psychedelic-Assisted Therapy in Rural Communities.Psychedelic medicine (New Rochelle, N.Y.) · 2025Article
- Psychedelic iatrogenic structural dissociation: an exploratory hypothesis on dissociative risks in psychedelic use.Frontiers in psychology · 2025Article
- Practical considerations in the establishment of psychedelic research programs.Psychopharmacology · 2025Review
- Protective Behavioral Strategies for Psychedelic Use: A Mini Review of the Evidence.Psychedelic medicine (New Rochelle, N.Y.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Though lysergic acid diethylamide (LSD) use is rising in the United States amid expanding research into the therapeutic potential of psychedelics, little scholarly work exists on whether perceived risk of trying LSD (prLSD) is changing or factors influencing prLSD among the general public. Therefore, we sought to investigate changes in prLSD from 2015 to 2019 and identify characteristics associated with prLSD among respondents to the National Survey on Drug Use and Health (NSDUH). Methods: Using NDSUH data from 2015 to 2019, we investigated correlates of and temporal trends in prLSD, reporting results for the entire sample, as well under age 18 (<18) and age 18 and older (18+) subgroups. Orthogonal polynomial contrasts were used to evaluate trends across survey years. Multivariable models were constructed to identify factors associated with prLSD. Results: On multivariable modeling for respondents age 18+, lower prLSD had statistically significant associations with later survey year, personal LSD use, younger age, higher education level, male gender, identifying as a sexual minority, past year psychological distress, and other factors. Higher prLSD was associated with identifying as Black or Hispanic, past year suicide attempt, and having children in the home. Notable differences in the age <18 subgroup were no association between prLSD and identifying as Hispanic and male gender being associated with higher prLSD. From 2015 to 2019, there was a statistically significant linear decreasing trend in proportion of respondents who perceived "great" risk in trying LSD [from 70.5% to 64.8%; ( Conclusions: We observed differences in prLSD among subgroups, suggesting that factors such as age, gender, race, ethnicity, and personal history of LSD may be related to prLSD. Overall, Americans appear to be assessing LSD's risk profile more favorably in recent years, though most Americans still perceive great risk in trying LSD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.