Evidence map›Paper›PMID 40051568›Full record

ArticleFrontiers in pharmacology2025

Luteolin inhibits diffuse large B-cell lymphoma cell growth through the JAK2/STAT3 signaling pathway.

Xin-Zhuo Zhan, Yi-Wen Bo, Yu Zhang, Hai-Dong Zhang, Zhi-Hao Shang, Hui Yu, Xiao-Li Chen, Xiang-Tu Kong, Wan-Zhou Zhao, Timo Teimonen and 5 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xin-Zhuo Zhan *Department of Hematology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Yi-Wen Bo *School of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Yu Zhang *School of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Hai-Dong ZhangDepartment of Hematology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Zhi-Hao ShangDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Hui YuDepartment of Hematology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Xiao-Li ChenDepartment of Hematology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Xiang-Tu KongDepartment of Hematology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Wan-Zhou ZhaoThe Nanjing Han & Zaenker Cancer Institute (NHZCI), OG Pharmaceuticals, Nanjing, Jiangsu, China.
Timo TeimonenAqsens Health Oy, Turku, Finland.
Tao LiuSchool of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Meng-Yi LuDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Ye YangSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Shan-Liang SunNational and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing, China.
Hai-Wen NiDepartment of Hematology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Luteolin, a flavonoid present in botanical drugs, plants, and dietary sources, has demonstrated anticancer properties against various tumors, yet its role in diffuse large B-cell lymphoma (DLBCL) remains unclear. This study aimed to uncover the molecular mechanism of luteolin in DLBCL treatment using a combination of

Indexed as

diffuse large B-cell lymphomaJanus kinase 2/signal transducer and activator of transcription 3luteolinmechanismtraditional Chinese medcine

Identifiers

PMID40051568
PMCPMC11882856

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.