Evidence map›Paper›PMID 40051509›Full record

ArticleFrontiers in public health2025

International perspectives on physician knowledge, attitudes, and practices related to medical cannabis.

Shariful A Syed, Jatinder Singh, Hussien Elkholy, Irena Rojnić Palavra, Marko Tomicevic, Anamarija Petek Eric, Mariana Pinto da Costa, Sinan Guloksuz, Rajiv Radhakrishnan

Abstract read
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Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Shariful A SyedDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, United States.
Jatinder SinghDepartment of Psychiatry, Penn State Milton S. Hershey Medical Center, Hershey, PA, United States.
Hussien ElkholyNeurology and Psychiatry Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Irena Rojnić PalavraUniversity Psychiatric Hospital Sveti Ivan, Zagreb, Croatia.
Marko TomicevicDepartment of Psychiatry, University Hospital Dubrava, Zagreb, Croatia.
Anamarija Petek EricDepartment of Psychiatry, Clinical Hospital Centre, Osijek, Croatia.
Mariana Pinto da CostaInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Sinan GuloksuzDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, United States.
Rajiv RadhakrishnanDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, United States.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Background: The trends of recreational use of cannabis and the use of cannabis for medical indications (i.e., "medical cannabis") have grown in recent years. Despite that, there is still limited scientific evidence to guide clinical decision-making, and the strength of evidence for the medical use of cannabis is currently considered to be low. In contrast, there is growing evidence of negative health outcomes related to the use of cannabis. In this rapidly shifting landscape, the role of physician attitudes regarding the therapeutic value of cannabis has become essential. This study aimed to characterize knowledge/experience, attitudes, and potential predictors of clinical practice regarding medical cannabis. Methods: We conducted a cross-sectional survey of physicians from 17 countries between 2016 and 2018. The survey consisted of questions designed to explore physician knowledge, attitude, and practices regarding the use of medical cannabis. Descriptive statistics were used to examine willingness to recommend medical cannabis for medical and psychiatric indications, followed by regression analysis to identify the predictors of physician willingness to recommend medical cannabis. Results: A total of 323 physicians responded to the survey, among which 53% were women. The mean age was 35.4 ± 9.5 years, with 10.04 ± 8.6 years of clinical experience. Clinical experience with medical cannabis was overall limited (51.4% noted never having recommended medical cannabis and 33% noted inadequate knowledge regarding medical cannabis). The majority of respondents (84%) recognized the risk of psychosis with cannabis use, while only 23% correctly identified the risk of addiction with daily cannabis use. Overall, willingness to recommend medical cannabis was the highest for chemotherapy-induced nausea (67%), refractory chronic neuropathic pain (52%), and spasticity in amyotrophic lateral sclerosis (ALS; 51%). Conclusion: This international study examining physician knowledge, attitudes, and practices related to medical cannabis revealed that there are significant gaps in domain-specific knowledge related to medical cannabis. There is a wide variability in willingness to recommend medical cannabis, which is not consistent with the current strength of evidence. This study thus highlights the need for greater education related to domain-specific knowledge about medical cannabis.

Indexed as

Attitude of Health PersonnelHealth Knowledge, Attitudes, PracticeInternationalityMedical MarijuanaPhysiciansPractice Patterns, Physicians'AdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesMedical Marijuanacannabis addictioncannabis psychosismedical cannabisphysician attitudephysician knowledgephysician practice

Identifiers

PMID40051509
PMCPMC11882600

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.