Evidence map›Paper›PMID 40051331›Full record

ArticleACS applied bio materials2025

From Unprintable Peptidic Gel to Unstoppable: Transforming Diphenylalanine Peptide (Fmoc-FF) Nanowires and Cellulose Nanofibrils into a High-Performance Biobased Gel for 3D Printing.

Feras Dalloul, J Benedikt Mietner, Dhanya Raveendran, Shouzheng Chen, Enguerrand Barba, Dennis M J Möck, Fabio Hubel, Benedikt Sochor, Sarathlal Koyiloth Vayalil, Linnea Hesse and 5 more

Abstract read
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. A simple, efficient technique to make colon crypt gels for 3D models.3D printing and additive manufacturing · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Feras DalloulInstitute of Wood Science, Universität Hamburg, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
J Benedikt MietnerInstitute of Wood Science, Universität Hamburg, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Dhanya RaveendranInstitute of Wood Science, Universität Hamburg, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Shouzheng ChenDeutsches Elektronen-Synchrotron DESY, Notkestrasse 85, 22607 Hamburg, Germany.
Enguerrand BarbaInstitute of Wood Science, Universität Hamburg, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Dennis M J MöckFederal Research Institute for Rural Areas, Forestry and Fisheries, Institute of Wood Research, Johann Heinrich von Thünen Institute, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Fabio HubelInstitute of Wood Science, Universität Hamburg, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Benedikt SochorDeutsches Elektronen-Synchrotron DESY, Notkestrasse 85, 22607 Hamburg, Germany.
Sarathlal Koyiloth VayalilDeutsches Elektronen-Synchrotron DESY, Notkestrasse 85, 22607 Hamburg, Germany.ORCID 0000-0003-3483-3310
Linnea HesseInstitute of Wood Science, Universität Hamburg, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Andrea OlbrichFederal Research Institute for Rural Areas, Forestry and Fisheries, Institute of Wood Research, Johann Heinrich von Thünen Institute, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Jörn AppeltFederal Research Institute for Rural Areas, Forestry and Fisheries, Institute of Wood Research, Johann Heinrich von Thünen Institute, Haidkrugsweg 1, 22885 Barsbüttel, Germany.
Peter Müller-BuschbaumDepartment of Physics, Chair for Functional Materials, TUM School of Natural Sciences, Technical University of Munich, James-Franck-Strasse 1, 85748 Garching, Germany.ORCID 0000-0002-9566-6088
Stephan V RothDeutsches Elektronen-Synchrotron DESY, Notkestrasse 85, 22607 Hamburg, Germany.
Julien R G NavarroInstitute of Wood Science, Universität Hamburg, Haidkrugsweg 1, 22885 Barsbüttel, Germany.ORCID 0000-0001-8791-6190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing interest in gel-based additive manufacturing, also known as three-dimensional (3D) gel-printing technology, for research underscores the crucial need to develop robust biobased materials with excellent printing quality and reproducibility. The main focus of this study is to prepare and characterize some composite gels obtained with a low-molecular-weight gelling (LMWG) peptide called Fmoc-diphenylalanine (Fmoc-FF) and two types of cellulose nanofibrils (CNFs). The so-called Fmoc-FF peptide has the ability to self-assemble into a nanowire shape and therefore create an organized network that induces the formation of a gel. Despite their ease of preparation and potential use in biological systems, unfortunately, those Fmoc-FF nanowire gel systems cannot be 3D printed due to the high stiffness of the gel. For this reason, this study focuses on composite materials made of cellulose nanofibrils and Fmoc-FF nanowires, with the main objective being that the composite gels will be suitable for 3D printing applications. Two types of cellulose nanofibrils are employed in this study: (1) unmodified pristine cellulose nanofibrils (uCNF) and (2) chemically modified cellulose nanofibrils, which ones have been grafted with polymers containing the Fmoc unit on their backbone (CNF-

Indexed as

Biocompatible MaterialsCelluloseDipeptidesNanofibersNanowiresPeptidesPhenylalaninePrinting, Three-DimensionalGelsMaterials TestingParticle SizeBiocompatible MaterialsCelluloseDipeptidesdiphenylalanineGelsPeptidesPhenylalanine3D gel printingcellulose nanofibrils (CNF)direct ink writing (DIW)Fmoc-FFnanocellulosesingle electron transfer living radical polymerization (SET-LRP)

Identifiers

PMID40051331
PMCPMC11921036

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.