Evidence map›Paper›PMID 40051084›Full record

ArticleAmerican journal of medical quality : the official journal of the American College of Medical Quality

Fragmented Ambulatory Care and Medication Count among Older Adults.

Indrani Guzman Das, Joanna Bryan Ringel, Mangala Rajan, Lisandro D Colantonio, Monika M Safford, Lisa M Kern

Abstract read
In one paragraph

Article in American journal of medical quality : the official journal of the American College of Medical Quality. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Indrani Guzman DasWeill Cornell Medicine, New York, NY.
Joanna Bryan RingelWeill Cornell Medicine, New York, NY.
Mangala RajanWeill Cornell Medicine, New York, NY.
Lisandro D ColantonioUniversity of Alabama at Birmingham, Birmingham, AL.
Monika M SaffordWeill Cornell Medicine, New York, NY.
Lisa M KernWeill Cornell Medicine, New York, NY.

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction-4 (REGARDS-MI-4)R01HL165452 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2022 to 2025
$8.3M
Healthcare Fragmentation and Cardiovascular OutcomesR01HL135199 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KERN, LISA M · 2017 to 2020
$3.3M
NHLBI NIH HHS R01 HL135199NHLBI NIH HHS R01 HL165452NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

This nationwide cross-sectional study explored the relationship between ambulatory care fragmentation and medication use in older US adults, examining variations by chronic conditions and race. Utilizing data from the 2003-2016 REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study linked with fee-for-service Medicare claims, the authors analyzed care fragmentation (measured by the reversed Bice-Boxerman Index) and medication counts through a 2-week in-person prescription inventory. They employed negative binomial regression, adjusting for potential confounders, and conducted subgroup analyses based on chronic conditions and race. Of the 4524 participants, 40.7% experienced high care fragmentation and 59.8% used 5 or more medications. High fragmentation was associated with a 4% overall increase in medication count ( P = 0.03), a 7% increase for those with 4+ chronic conditions ( P = 0.01), and a 9% increase for Black participants ( P = 0.01). In conclusion, fragmented care is independently associated with greater polypharmacy, particularly among Black older adults and those with multiple chronic conditions.

Indexed as

Ambulatory CarePolypharmacyAgedAged, 80 and overBlack or African AmericanChronic DiseaseCross-Sectional StudiesFemaleHumansMaleMedicareUnited StatesWhiteambulatory carefragmentationmedicaremedicationpolypharmacy

Identifiers

PMID40051084
PMCPMC12168246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.