Evidence map›Paper›PMID 40051047›Full record

ReviewRNA biology2025

Noncoding function of super enhancer derived

Bingning Xie, Ann Dean

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Bingning XieLaboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0009-0001-1505-4701
Ann DeanLaboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-6558-747X

Funding

Epigenetic and Developmental Regulation of Mammalian GenesZIADK075033 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI DEAN, ANN · 2009 to 2025
$24.2M
Intramural NIH HHS ZIA DK075033
6 · The paper itself

Abstract

Super enhancers are important regulators of gene expression that often overlap with protein-coding genes. However, it is unclear whether the overlapping protein-coding genes and the RNA derived from them contribute to enhancer activity. Using an erythroid-specific super enhancer that overlaps the

Indexed as

ChromatinEnhancer Elements, GeneticGene Expression RegulationRNA PrecursorsE1A-Associated p300 ProteinHistonesHumansSuper EnhancersChromatinE1A-Associated p300 ProteinHistonesRNA Precursorschromatin regulationChromatin structuregene silencingInter-gene interactiononcogenesuper enhancerTAD boundary

Identifiers

PMID40051047
PMCPMC11913378

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.