Evidence map›Paper›PMID 40050993›Full record

Observational studyWorld journal of emergency surgery : WJES2025

Safety and efficacy of prophylactic onlay resorbable synthetic mesh with a comprehensive wound bundle at laparotomy closure in high-risk emergency abdominal surgery: an observational study.

Emily Kelly, Angus Lloyd, Daniah Alsaadi, Ian Stephens, Michael Sugrue

Abstract readObservational Study
In one paragraph

Observational study in World journal of emergency surgery : WJES, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emily KellySchool of Medicine, College of Medicine, Nursing & Health Sciences, University of Galway, Galway, Ireland. emilykellyresearch@gmail.com.
Angus LloydDepartment of Surgery, Letterkenny University Hospital, Letterkenny, Donegal, Ireland.
Daniah AlsaadiClinical Research Facility Galway, University Hospital Galway, University of Galway, Galway, Ireland.
Ian StephensSchool of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, 123 St. Stephen's Green, Dublin 2, Dublin, Ireland.
Michael SugrueDonegal Clinical Research Academy, Letterkenny University Hospital, Letterkenny, Donegal, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been a slow uptake of wound bundles and prophylactic mesh augmentation (PMA) strategies despite evidence supporting their role in reducing burst abdomens and incisional hernias (IH). This study evaluates outcomes of resorbable synthetic prophylactic mesh augmentation in reducing these rates and assesses the complication profile in emergency abdominal surgery.

methodsA retrospective ethically approved observational study of all patients who underwent emergency open abdominal surgery using supplemental prophylactic onlay TIGR

resultsOf the 49 patients included, the mean age was 64 years (± 16.4, 31-86), 33/49 (67%) were female, and the mean body mass index (BMI) was 27 (± 7.4,17.3-45). 20% of patients had previous abdominal surgery. 19/49 (38%) patients experienced postoperative complications, of these 8 (42%) were Clavien-Dindo Grade I-II, and 11 (58%) were Grade III-IV. There were 7 in-hospital post-operative deaths (Grade V). 8 patients had open abdomens. Thirteen surgical site occurrences (SSO) were identified in 9 (18%) patients. There were no burst abdomens. Four of the superficial SSIs responded to antibiotics while one required opening and wound NPWT. Three patients (6%) developed an incisional hernia, which was detected at a mean follow-up of 353 days.

conclusionA comprehensive, evidence-based wound bundle using onlay PMA with a synthetic resorbable mesh, achieves efficacious, safe abdominal wall closure in high-risk, emergency laparotomy patients, including those who require delayed abdominal wall closure.

Indexed as

Abdominal Wound Closure TechniquesLaparotomySurgical MeshAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesEmergency laparotomyIncisional herniaOnlay meshProphylactic meshSeromaSurgical site infectionTIGRWound bundleWound dehiscence

Identifiers

PMID40050993
PMCPMC11884156

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.