Evidence map›Paper›PMID 40050989›Full record

ArticleJournal of orthopaedic surgery and research2025

Relationship between anterior or posterior femoral head necrosis and collapse based on MRI-defined key necrotic layer sets.

Yawei Dong, Yan Yan, Jun Zhou, Kaiqiang Tang, Xiaohan Wang, Rui Quan, Jiaming Lin, Yan Jia, Zelu Zheng, Baohong Mi and 1 more

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. [Finite element analysis of CT-based lateral classification of Japanese Investigation Committee type C1 osteonecrosis of femoral head and its prognostic value].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yawei Dong *The Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Yan Yan *The Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Jun ZhouThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Kaiqiang TangThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Xiaohan WangThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Rui QuanThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Jiaming LinThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Yan JiaThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Zelu ZhengThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China.
Baohong MiThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China. mibaohong12587@163.com.
Weiheng ChenThe Third Affiliated Hospital of Beijing University of Chinese Medicine, NO.51, Xiaoguan Street, Chaoyang District, Beijing, China. drchenweiheng@bucm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent clinical studies on femoral head necrotic lesions primarily focus on the medial and lateral regions, while detailed MRI-based methods to evaluate the relationship between anterior or posterior necrosis and collapse remain lacking.

objectiveBy defining the anterior and posterior positions of the femoral head in MRI, a method was proposed for rapid clinical prognosis assessment of femoral head necrosis based on necrotic location. METOHD: A retrospective analysis was conducted on TSE sequence T1W1 coronal plane images from 200 cases of femoral head necrosis. The frequency of necrotic lesions appearing on each MRI layer was statistically analyzed to construct a high-frequency necrotic layer set. Among these cases, 100 hips were randomly selected, and the relationship between femoral head collapse at one-year follow-up and different high-frequency necrotic layer sets was analyzed to identify the key necrotic layer set. Based on this, the anterior and posterior regions of the femoral head were defined on MRI. The remaining 100 hips were used as a validation set to assess the impact of anterior or posterior necrosis of the femoral head, as defined by this method, on collapse.

resultsIn this study, a total of eight high-frequency necrotic lesion layer sets (S1-S8) were constructed based on MRI data. Among them, S3 (L1 + L2 + L0 + L3) showed the strongest correlation with femoral head collapse, with an AUC of 0.662. Therefore, S3 was defined as the anterior side of the femoral head. Analysis of the validation set revealed that, using this method, the probability of femoral head collapse was 11.4 times higher when necrotic lesions appeared on the anterior side compared to the absence of necrosis on the anterior side.

conclusionIn MRI, the anterior side of the femoral head corresponds to the S3 region, where necrosis increases the risk of collapse by 11.4 times.

Indexed as

Femur HeadFemur Head NecrosisMagnetic Resonance ImagingAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesYoung AdultLocatipn of necrotic lesionsMagnetic resonance imagingOsteonecrosis of femoral headPrediction of collapse

Identifiers

PMID40050989
PMCPMC11887068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.