Evidence map›Paper›PMID 40050850›Full record

ArticleBMC psychiatry2025

Interoception as a key node in the multidimensional psychological structural model of depression: a structural equation model analysis of integrating environmental, cognitive and behavioral-emotional factors.

Jikang Liu, Jiaxu Li, Tiantian Wang, Yuqing Wu, Xiaohong Liu, Xuezheng Gao, Zhenhe Zhou, Hongliang Zhou

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In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jikang Liu *Department of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi City, 214151, China.
Jiaxu Li *Department of Psychiatry, Wuxi Mental Health Center, Training Base of Hubei University of Medicine, Shiyan, Hubei Province, 442000, China.
Tiantian Wang *Department of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, Wuxi City, 214151, China.
Yuqing WuDepartment of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, Wuxi City, 214151, China.
Xiaohong LiuDepartment of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi City, 214151, China.
Xuezheng GaoDepartment of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi City, 214151, China.
Zhenhe ZhouDepartment of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi City, 214151, China. zhouzh@njmu.edu.cn.
Hongliang ZhouDepartment of Psychology, The Affiliated Hospital of Jiangnan University, Wuxi City, 214151, China. Hongliangzh@jiangnan.edu.cn.

Funding

Wuxi Municipal Health Commission Major Project No. 202107Wuxi Taihu Talent Project No. WXTTP 2021
6 · The paper itself

Abstract

backgroundThe psychological structural model of major depressive disorder (MDD) is complex and multifaceted, consisting of the environment factors (EF), cognitive function (CF), and behavioral-emotional manifestations (BEM). Currently, the diagnosis and treatment of MDD is difficult to improve the disease state as a whole through an intervention point. Constructing the psychological structural model of MDD and finding the critical node of the psychological structural model are meaningful for the diagnosis and treatment of MDD.

methods308 MDD patients (MDDs) participated in this research. They completed assessments of 34 psychological factors, including EF, CF, BEM and interoception function (IF). Pearson correlation was used to investigate the relationship between IF and each factor in the depressive multidimensional psychological structural model (EF, CF and BEM) which was constructed by structural equation modeling (SEM). Critical nodes were identified by the goodness of fit of the model. The depressive multidimensional psychological structural model (EF, CF and BEM) was created through SEM. IF was added to the depressive multidimensional psychological structural model to further verify the pathways and effects of interoception in the network.

resultsIF was significantly correlated with all psychological factors. In the depressive multidimensional psychological structural model, EF (β

conclusionsIF is a part of the psychological structural model of MDD that predicts EF, CF, and BEM. It could be a potential intervention point to improve the depressive state as a whole.

Indexed as

CognitionEmotionsInteroceptionMajor Depressive DisorderModels, PsychologicalAdultFemaleHumansLatent Class AnalysisMaleMiddle AgedYoung AdultBehavioral-emotional manifestationsCognitive functionEnvironmental factorsInteroception functionMajor depressive disorderStructural equation modeling

Identifiers

PMID40050850
PMCPMC11887121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.