SynthesisBMC oral health2025
The relationship between adequate keratinized mucosa and peri-implant disease: a systematic review and meta-analysis.
Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Keratinized Mucosa Width and Incidence of Peri-Implant Diseases: A Systematic Review With Meta-Analysis.Journal of periodontal research · 2026Pooled it
- Wound Healing Patterns of PRF and PRGF Versus a Collagen-Based Substitute and Spontaneous Healing-A Randomised Controlled Clinical Trial Assessing Wound Closure of an Experimental, Standardised Palatal Defect.Journal of clinical periodontology · 2026Trial
- Trial
- Modified Neumann incision for implant placement in overdentures: Case series of a less invasive alternative.Clinical advances in periodontics · 2026Article
- The Role of the Keratinized Mucosa in Peri-Implant Diseases Onset and Brushing Discomfort: A 10-Year Follow-Up.Clinical oral implants research · 2026Article
- Article
- Soft Tissue Augmentation in Periodontics and Implantology: Current Concepts, Techniques, and Clinical Outcomes.Cureus · 2026Review
- Minimally invasive management of lower midline diastema: A case report and literature review.Medicine · 2026Review
- Shallow vestibular depth as a risk indicator for peri-implantitis: a retrospective analysis of 336 implants.Clinical oral investigations · 2026Review
- Peri-Implantitis-An Overview of Treatment Options and a New Approach to the Treatment of Peri-Implantitis Using a Magnesium Membrane in Three Case Reports.Dentistry journal · 2026Review
- Evaluation of soft tissue outcomes following keratinized tissue augmentation around dental implants using free gingival graft and xenogenic collagen matrix: A randomized clinical study.Bioinformation · 2026Article
- Two-Step Palatal Shield Technique Using Flowable Composite Resin for Donor-Site Protection Following De-Epithelialized Free Gingival Grafting: A Case Report Illustrating a Novel Technique.Case reports in dentistry · 2026Article
- Keratinized Mucosa Width and Peri-Implant Health: Clinical Associations to Inform Soft Tissue Evaluation.International journal of dentistry · 2026Article
- Horizontal Bone Augmentation with Natural Collagen Porcine Pericardium Membranes: A Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2025Article
- The Application of a Flowable Composite as a Method for Donor Site Protection After Free Gingival Graft: A Comparative Analysis of Four Techniques.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundControversial conclusions have been drawn from recent researches that examined the impact of keratinized mucosa width on clinical parameters of peri-implant health status. The purpose of this meta-analysis is to assess the effect of keratinized mucosa width on these clinical parameters by combining data from different studies.
methodsA systematic literature search was performed using PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and VIP Data from the beginning of the database until May 2024. Mean difference (MD) along with the 95% confidence interval (CI) were calculated for plaque index (PI), gingival index (GI), bleeding index (BI), probing depth (PD), clinical attachment level (CAL) and bone loss (BL). The Q test and I
resultsA total of 30 articles were included for meta-analysis. Implants with adequate width of keratinized mucosa (≥ 2 mm) presented significantly reduced PI (MD: -0.30, 95% CI: -0.42 to -0.17), GI (MD: -0.26, 95% CI: -0.38 to -0.13), BI (MD: -0.20, 95% CI: -0.33 to -0.07), and BL (MD: -0.27, 95% CI: -0.42 to -0.12). Although significant heterogeneity was detected among the included studies, sensitivity analysis further demonstrated the robustness of the results.
conclusionsThe meta-analysis demonstrated that adequate width of keratinised mucosa (≥ 2 mm) around dental implants is associated with reduced plaque accumulation, tissue inflammation, and bone loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.