ArticleBMC plant biology2025
The CGA1-SNAT regulatory module potentially contributes to cytokinin-mediated melatonin biosynthesis and drought tolerance in wheat.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- DcGATA22 serves as a transcription factor positively coordinating chlorophyll and carotenoid accumulation in carrot.Planta · 2026Article
- Integrative multi-scale analysis reveals a candidate melatonin receptor associated with early salinity response networks in barley.Scientific reports · 2026Article
- UHPLC-MS/MS, transcriptomic, and genomic analyses unravel the molecular mechanism on melatonin biosynthesis in Tartary buckwheat sprouts.Food chemistry. Molecular sciences · 2026Article
- Melatonin enhances the cold tolerance of tomatoes by promoting ABA accumulation.Plant cell reports · 2026Article
- Effects of Different Plant Growth Regulators on Growth Physiology and Photosynthetic Characteristics ofPlants (Basel, Switzerland) · 2025Article
- Identification of key pathways and genes underlying melatonin-enhanced drought tolerance in cotton.PeerJ · 2025Article
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Authors and funding
3 authors.
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Abstract
backgroundMelatonin plays a pivotal role in alleviating abiotic stresses, yet its biosynthesis regulation in crops, particularly wheat, remains unclear. This study explores regulatory components of melatonin biosynthesis under drought stress using bioinformatic, physiochemical, and molecular approaches in contrasting wheat genotypes.
resultsBioinformatic analysis identified SNAT, a key melatonin biosynthesis gene, and 88 transcription factors (TFs) from 26 families as potential regulators. The regulatory network for SNAT highlighted CYTOKININ-RESPONSIVE GATA FACTOR 1 (CGA1) as a significant TF. Under drought stress, contrasting wheat genotypes exhibited distinct CGA1-SNAT module expression, melatonin and cytokinin levels, photosynthetic activity, and oxidative damage. Cytokinin treatments regulated the CGA1-SNAT module, altering melatonin content, SPAD values, and chloroplast numbers, particularly in drought-susceptible genotypes.
conclusionsThis study uncovers the pivotal role of the CGA1-SNAT module and its interaction with the cytokinin pathway in regulating melatonin biosynthesis during drought stress. These findings enhance our understanding of the molecular mechanisms underpinning drought tolerance and offer promising targets for genetic and biochemical interventions to improve crop resilience.
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