Evidence map›Paper›PMID 40050780›Full record

ArticleBMC infectious diseases2025

Implementation of an infection prevention and control response strategy to combat the Sudan Virus Disease outbreak in an urban setting, the Kampala Metropolitan area, Uganda, 2022.

S Judith Nanyondo, Shillah Nakato, Janelle Franklin, Andrew Kwiringira, Marvin Malikisi, Maureen Kesande, Abdullah Wailagala, Rebecca Suubi, Dathan M Byonanebye, Elizabeth Katwesigye and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

S Judith NanyondoInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda. nsjudytah@gmail.com.
Shillah NakatoInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.
Janelle FranklinUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Andrew KwiringiraInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.
Marvin MalikisiInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.
Maureen KesandeInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.
Abdullah WailagalaInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.
Rebecca SuubiInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.
Dathan M ByonanebyeInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.
Elizabeth KatwesigyeMinistry of Health (MoH), Kampala, Uganda.
Paul KatongoleSchool of Public Health, Makerere University, Kampala, Uganda.
Juliet KasuleUS Centers for Disease Control and Prevention (CDC), Kampala, Uganda.
Louis B BayoFamily Health International (FHI 360), Kampala, Uganda.
Martin KasendwaFamily Health International (FHI 360), Kampala, Uganda.
Diriisa MusisiUS Centers for Disease Control and Prevention (CDC), Kampala, Uganda.
Jennifer HunterUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Lisa P OakleyUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Cori DennisonUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Linus NdegwaUS Centers for Disease Control and Prevention (CDC), Nairobi, Kenya.
Lindsay K TompkinsUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Neil GuptaUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Rony BahatungireMinistry of Health (MoH), Kampala, Uganda.
Victoria WilletWorld Health Organization (WHO), Geneva, Switzerland.
Amy R KolwaiteUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Sarah ZalwangoKampala City Council Authority (KCCA), Kampala, Uganda.
Elizabeth BancroftUS Centers for Disease Control and Prevention (CDC), Atlanta, USA.
Stacey MearnsResolve to Save Lives, New York, USA.
Mohammed LamordeInfectious Diseases Institute (IDI), College of Health Sciences, Makerere University, Kampala, Uganda.

Funding

Centres for Disease Control and Prevention(CDC), United States GH000045World Health Organization 001
6 · The paper itself

Abstract

backgroundIn October 2022, the Uganda Ministry of Health (MoH) confirmed the first case of a Sudan Virus Disease (SVD) outbreak in the Kampala Metropolitan area (KMA). A multicomponent infection prevention and control (IPC) strategy was implemented to control the spread of Orthoebolavirus sudanense (SUDV) in KMA. We describe the deployment of this strategy, its effect on IPC capacities, and the successful control of the SVD outbreak in KMA during the 2022 outbreak. METHODOLOGY: The multicomponent IPC strategy included (1) IPC pillar coordination: an IPC task force convened by government and health partner representatives and designated focal persons at the district level (2) Ring IPC: intense and targeted IPC support was developed to provide support to healthcare facilities (HCFs) and communities around each confirmed case, (3) IPC in HCFs: HCFs were assessed using a modified WHO SVD IPC scorecard rapid assessment tool that measured 15 IPC capacity domains, mentorship and IPC supplies were provided to HCFs with low scores on the rapid assessment.

resultsA KMA task force was established, and 13 IPC Rings were activated; 790 HCFs were assessed for IPC readiness, and 2,235 healthcare workers (HCWs) were trained. The mean (± standard-deviation) IPC score was 59.2% (± 18.6%) at baseline and increased to 65.5% (± 14.7%) at follow-up after 2 weeks (p < 0.001) of support. The mean IPC scores at baseline were lowest for primary HCFs (57%) and private-for-profit HCFs (47.1%). Similar gaps were revealed across all HCFs, with eight out of 15 (53.3%) IPC capacity areas assessed, resulting in scores < 50% at baseline. At follow-up, only four out of 15 (26.7%) capacity areas (26.7%) were below this threshold.

conclusionThe IPC strategy enhanced the IPC capacities at HCFs and could be adopted for future outbreaks. Leadership commitment and resource allocation to IPC during non-outbreak periods are critical for preparedness, rapid response, and access to safe care.

Indexed as

Disease OutbreaksHemorrhagic Fever, EbolaInfection ControlHumansSudanUgandaUrban PopulationEbolaInfection prevention and controlOrthoebolavirus sudanenseOutbreak responseRing IPCSudan Virus DiseaseUganda

Identifiers

PMID40050780
PMCPMC11883975

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.