ArticleBMC medical imaging2025
Magnetic resonance diffusion-derived vessel density (DDVD) as a valuable tissue perfusion biomarker for isocitrate dehydrogenase genotyping in diffuse gliomas.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Preoperative Prediction of Lymphovascular Space Invasion in Endometrial Cancer Using Diffusion MRI-Derived Vessel Density.Korean journal of radiology · 2026Article
- Classification of hepatocellular carcinoma Ki-67 expression status by a simple combination of magnetic resonance slow diffusion coefficient (SDC) and apparent diffusion coefficient (ADC): initial promising results.Quantitative imaging in medicine and surgery · 2026Article
- Higher perfusion among breast malignant tumors than among breast benign lesions as demonstrated by diffusion-derived 'vessel density' (DDVD): a pilot study.Quantitative imaging in medicine and surgery · 2026Article
- A novel MRI diffusion metric 'slow diffusion coefficient' (SDC) for diagnosing isocitrate dehydrogenase (IDH) genotype in diffuse gliomas: initial promising results.BMC medical imaging · 2025Article
- Lower diffusion-derived vessel density (DDVD) measure of liver focal nodular hyperplasia than those of hepatocellular carcinoma and liver metastasis allows potential differential diagnosis: quantitative and semi-quantitative analyses of two-center data.Journal of gastrointestinal oncology · 2025Article
- Article
- The relevance of placenta MRI diffusion-derived vessels density and morphological features in diagnosing placenta accreta spectrum.BMC medical imaging · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundDetermining isocitrate dehydrogenase (IDH) mutation is crucial for glioma clinical management. MR diffusion-derived 'vessel density' (DDVD) offers non-invasive tissue perfusion evaluation within the tumor microenvironment. The study attempts to distinguish IDH genotypes of diffuse gliomas using DDVD in whole tumor parenchyma and its habitats.
methodsThis study enrolled 63 patients with diffuse gliomas (30 IDH-mutant and 33 IDH-wildtype) who underwent diffusion-weighted (DW) imaging at 3T. DDVD
resultsIn tumor parenchyma, DDVD
conclusionDDVD, as a novel biomarker of microvascular perfusion, effectively differentiates IDH genotypes in gliomas. The habitat analysis improves the diagnostic accuracy for IDH genotyping.
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