Evidence map›Paper›PMID 40050539›Full record

ReviewCurrent topics in behavioral neurosciences2025

How Early-Life Antipsychotic Drug Administration Modifies Behavioral and Brain Function in Adulthood.

Mark E Bardgett

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in behavioral neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Long-term effects of adolescent risperidone treatment on the mouse cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mark E BardgettDepartment of Psychological Science, Northern Kentucky University, Highland Heights, KY, USA. bardgettm@nku.edu.

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
Brain Development after Early-Life Antipsychotic TreatmentR16GM149498 · NIGMS · NORTHERN KENTUCKY UNIVERSITY · PI MARK Edward BARDGETT · 2023 to 2026
$548k
NIGMS NIH HHS P20 GM103436NIGMS NIH HHS R16 GM149498
6 · The paper itself

Abstract

The use of antipsychotic drugs in children has greatly expanded over the past 30 years. This increase occurred despite a lack of research addressing how these drugs affect brain development. This review summarizes and synthesizes preclinical studies that have ascertained the short- and long-term consequences of prenatal and early postnatal antipsychotic drug administration. Antipsychotic drugs are well-known for their ability to block D

Indexed as

Antipsychotic AgentsBrainPrenatal Exposure Delayed EffectsAnimalsFemaleHumansPregnancyAntipsychotic AgentsAtypicalChildrenD2 receptorDopamineForebrainHaloperidolOlanzapinePostnatalPrenatalRatRisperidoneTypical

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.