ArticleDermatology and therapy2025
Life-Changing Decisions in Patients Suffering from Psoriasis: A Cross-Sectional Study.
Article in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Hidradenitis Suppurativa Changes Major Life Decisions of Affected Patients: A Cross-sectional Study.Acta dermato-venereologica · 2026Article
- Uncovering the Life-long Impact of Skin Disease on Major Life Changing Decisions.Acta dermato-venereologica · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPsoriasis is a chronic inflammatory skin disease affecting over 60 million people worldwide, often linked to comorbidities such as psoriatic arthritis and cardiovascular disease. Beyond physical symptoms, psoriasis can significantly impact major life-changing decisions (MLCDs), leading to long-term consequences and missed opportunities. This study focused on assessing MLCDs and their correlations with quality of life (QoL), disease acceptance, and itch severity, emphasizing the need for early intervention to mitigate cumulative life course impairment.
methodsA total of 166 consecutive patients with psoriasis, comprising 101 men and 65 women, all with a minimum disease duration of 1 year, were included in the study. Clinical and psychological aspects of psoriasis were thoroughly evaluated using a range of standardized instruments, along with a questionnaire collecting demographic data.
resultsPsoriasis affected at least one MLCD in 93.4% of patients, most commonly influencing decisions related to physical activity (77%), dietary habits (70%), smoking and alcohol consumption (58%), and job choices (30%). A significant correlation was found between the Major Life-Changing Decisions Profile (MLCDP) total score and QoL (r = 0.561, p < 0.001), psoriasis severity (r = 0.275, p < 0.001), and itch severity (r = 0.351, p < 0.001), as well as an inverse correlation with disease acceptance (r = - 0.545, p < 0.001).
conclusionPsoriasis may affect MLCDs, reflecting the long-term consequences of the disease. A comprehensive approach is essential to prevent these impacts, especially in cases of early-onset psoriasis.
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