Evidence map›Paper›PMID 40050507›Full record

Trial reportLasers in medical science2025

Effects of 3.95 μm infrared moxibustion on cancer-related fatigue: a randomized, controlled trial.

Dan Li, Baixiao Zhao, Fengli Jiang, Kaiwen Hu, Li Han, Xiaojun Li, Yi Xu, Yao Lin, Nini Zhangyang, Xingpong Chen and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. From traditional warming and tonifying to psychoneuroimmunology: theoretical reconstruction and clinical application of moxibustion for cancer-related fatigue.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dan LiDepartment of Traditional Chinese Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China.
Baixiao ZhaoSchool of Acupuncture and Tuina, Beijing University of Traditional Chinese Medicine, Beijing, China. baixiao100@vip.sina.com.
Fengli JiangDepartment of Hepatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing University of Traditional Chinese Medicine, Chongqing, China.
Kaiwen HuDepartment of Oncology, Oriental Hospital, Beijing University of Traditional Chinese Medicine, Beijing, China.
Li HanDepartment of Health Rehabilitation, School of Traditional Chinese Medicine, Beijing University of Traditional Chinese Medicine, Beijing, China.
Xiaojun LiDepartment of Traditional Chinese Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China.
Yi XuDepartment of Traditional Chinese Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China.
Yao LinSchool of Acupuncture and Tuina, Beijing University of Traditional Chinese Medicine, Beijing, China.
Nini ZhangyangSchool of Acupuncture and Tuina, Beijing University of Traditional Chinese Medicine, Beijing, China.
Xingpong ChenSchool of Traditional Chinese Medicine, Beijing University of Traditional Chinese Medicine, Beijing, China.
Yifan WangThe First Clinical School of Medicine, Beijing University of Traditional Chinese Medicine, Beijing, China.

Funding

the National major R &D plan of China 2019YFC1711904
6 · The paper itself

Abstract

Cancer-related fatigue(CRF) is a prevalent and distressing symptom among cancer patients. This study aimed to assess the initial effectiveness and safety of 3.95 μm infrared moxibustion for CRF. A randomized controlled trial was conducted with 65 CRF-diagnosed cancer patients, where the treatment group received 3.95 μm infrared moxibustion on on the ST36 (bilateral), CV4, and CV6 acupoints, each patient underwent 30-minute sessions, with 8 sessions per course and a total of 24 sessions, while the control group received standard care. The study evaluated fatigue and sleep quality using the Piper Fatigue Score (PFS) and the Pittsburgh Sleep Quality Index (PSQI) after the 2nd and 3rd sessions. After the 2nd session, individual fatigue was significantly lower in the infrared moxibustion treatment group than in the control group (6.39 vs. 5.26, P = 0.000). After the 3rd session, individuals treated with infrared moxibustion had significantly better fatigue and sleep quality than the control group (6.60 vs. 4.63, P = 0.000), (9.45 vs. 7.84, P = 0.041). The safety profile of infrared moxibustion was favorable, with only four cases of skin adverse reactions reported. This study suggests that infrared moxibustion is a safe and effective treatment for CRF in Chinese cancer patients. However, further research involving larger and more diverse populations is necessary to validate these findings.

Indexed as

FatigueInfrared RaysMoxibustionNeoplasmsAcupuncture PointsAdultAgedFemaleHumansMaleMiddle AgedSleep QualityCancer-related fatigueClinical trialInfraredMoxibustion

Identifiers

PMID40050507
PMCPMC11885316

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.