Evidence map›Paper›PMID 40050432›Full record

ArticleNature immunology2025

The integrated stress response pathway controls cytokine production in tissue-resident memory CD4

Nariaki Asada, Pauline Ginsberg, Hans-Joachim Paust, Ning Song, Jan-Hendrik Riedel, Jan-Eric Turner, Anett Peters, Anna Kaffke, Jonas Engesser, Huiying Wang and 13 more

Abstract read
In one paragraph

Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Pareto optimality reveals an atlas of cellular archetypes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  11. Article
  12. Primary Metabolites in ThreeLife (Basel, Switzerland) · 2026
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Memory CD4Frontiers in immunology · 2026
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Nariaki AsadaIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-5659-2944
Pauline GinsbergIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hans-Joachim PaustIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ning SongIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jan-Hendrik RiedelIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jan-Eric TurnerIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-1677-5455
Anett PetersIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anna KaffkeIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jonas EngesserIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Huiying WangIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Yu ZhaoIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0003-2632-7530
Robin KhatriIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0009-0006-5311-1718
Philipp GildDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Roland DahlemDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Björn-Philipp DiercksThe Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-6635-1706
Sarada DasInstitute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0002-6595-533X
Zoya IgnatovaInstitute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0002-9478-8825
Tobias B HuberIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-7175-5062
Immo PrinzHamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nicola GaglianiHamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-8514-1395
Hans-Willi MittrückerHamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-6166-4191
Christian F KrebsIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0003-2739-5578
Ulf PanzerIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. panzer@uke.uni-hamburg.de.ORCID http://orcid.org/0000-0001-9449-0722

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) SFB 1192
6 · The paper itself

Abstract

Tissue-resident memory T (T

Indexed as

CD4-Positive T-LymphocytesCytokinesImmunologic MemoryMemory T CellsStress, PhysiologicalAnimalsEukaryotic Initiation Factor-2FemaleHumansLymphocyte ActivationMaleMiceMice, Inbred C57BLMice, KnockoutRNA, MessengerSignal TransductionCytokinesEukaryotic Initiation Factor-2RNA, Messenger

Identifiers

PMID40050432
PMCPMC11957990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.