Evidence map›Paper›PMID 40050250›Full record

ArticleRenal failure2025

Risk factors for IgA nephropathy recurrence and impact on graft survival in a cohort of kidney transplanted patients.

Angelodaniele Napoletano, Michele Provenzano, Federica Maritati, Valeria Corradetti, Vania Cuna, Elisa Gessaroli, Chiara Abenavoli, Simona Barbuto, Marcello Demetri, Matteo Ravaioli and 2 more

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angelodaniele NapoletanoNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Michele ProvenzanoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, CS, Italy.
Federica MaritatiNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Valeria CorradettiNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Vania CunaNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Elisa GessaroliNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Chiara AbenavoliNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Simona BarbutoNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Marcello DemetriDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Matteo RavaioliDepartment of Medical and Surgical Sciences, University of Bologna, Italy.
Giorgia ComaiNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.
Gaetano La MannaNephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Univesitaria di Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrence of IgA nephropathy (IgAN) after kidney transplant (KT) appears associated with worse graft survival; thus, the identification of risk factors is worthwhile to improve pre-transplant evaluation of KT recipients and to identify the optimal treatment strategy. The aim of this study was to determine incidence, risk factors and impact on renal function and graft survival of IgAN recurrence after KT. We performed a retrospective study including 110 patients with biopsy-proven IgAN, who underwent KT at Policlinico di Sant'Orsola Hospital - University of Bologna from 2005 to 2021. IgAN recurred in 14 patients (12.7%) with a median time-to-recurrence of 59 (16-90) months. We found that a faster progression from IgAN diagnosis to end-stage kidney disease (ESKD), a younger age at ESKD, and a younger age at KT were associated with a higher risk of recurrence. During the first 2 years after KT, 24 h proteinuria was higher in patients with IgAN recurrence than in patients without (0.40 (0.11-1.8) vs 0.22 (0.18-0.37) g/day,

Indexed as

Glomerulonephritis, IGAGraft SurvivalKidney Failure, ChronicKidney TransplantationAdultAge FactorsDisease ProgressionFemaleGlomerular Filtration RateHumansIncidenceMaleMiddle AgedProteinuriaRecurrenceRetrospective Studiesgraft survivalIgA nephropathyIgAN recurrencekidney transplantationrisks factors

Identifiers

PMID40050250
PMCPMC11892068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.