ArticleBMJ open2025
Effect of driving pressure-guided individualised positive end-expiratory pressure on postoperative atelectasis in patients with morbid obesity: study protocol of a randomised controlled trial.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06181279 (Effects of Individualized Positive End-expiratory Pressure Guided by Driving Pressure on Postoperative Atelectasis After Bariatric Surgery in Patients With Morbid Obesity), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Individualized Positive End-expiratory Pressure Guided by Driving Pressure on Postoperative Atelectasis After Bariatric Surgery in Patients With Morbid Obesity: A Single-center, Prospective, Randomized Controlled Study
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7 authors.
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Abstract
introductionAtelectasis is a common postoperative complication in patients with obesity, contributing to respiratory insufficiency, pneumonia and poor clinical outcomes. Studies have shown that driving pressure (DP)-guided individualised positive end-expiratory pressure can improve respiratory mechanics and oxygenation, while also reducing the incidence of atelectasis and other postoperative pulmonary complications (PPCs). However, the effect of this ventilation strategy on patients with morbid obesity remains unclear. The trial presented here aims to use lung ultrasound to evaluate the effect of DP-guided individualised positive end-expiratory pressure (PEEP) on postoperative atelectasis in patients with obesity undergoing bariatric surgery. METHODS AND ANALYSIS: This single-centre, randomised, controlled, single-blind study will enrol 52 participants with morbid obesity scheduled for laparoscopic bariatric surgery from 1 March 2024, to 30 April 2025. They will be randomly assigned in a 1:1 ratio to one of two groups: (1) the DP group, where participants will receive dynamic individualised PEEP guided by DP and (2) the fixed PEEP group, where participants will receive a PEEP of 8 cmH ETHICS AND DISSEMINATION: This study has been approved by the Ethics Committee of The First Affiliated Hospital of Shandong First Medical University (YXLL-KY-2023(144)). The trial results will be published in peer-reviewed journals and at conferences. TRIAL REGISTRATION NUMBER: https://clinicaltrials.gov/; NCT06181279.
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