Evidence map›Paper›PMID 40050006›Full record

Observational studyEmergency medicine journal : EMJ2025

Reducing time delays and enhancing reperfusion eligibility related to stroke suspicion by the Emergency Medical Dispatch Centre: a registry-based observational study.

Nedim Leto, Elisabeth Farbu, Paul Barach, Michael Busch, Helene Lund, Conrad Arnfinn Bjørshol, Martin Kurz, Annette Fromm, Øyvind Østerås, Linn Therese Hagen and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Emergency medicine journal : EMJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nedim LetoDepartment of Clinical Medicine, University of Bergen, Bergen, Norway nedim.leto@sus.no.ORCID http://orcid.org/0000-0002-7435-5344
Elisabeth FarbuDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Paul BarachThomas Jefferson University, Philadelphia, Pennsylvania, USA.
Michael BuschRegional Centre for Emergency Medical Research and Development in Western Norway (RAKOS), Stavanger, Norway.
Helene LundStavanger University Hospital, Stavanger, Norway.
Conrad Arnfinn BjørsholDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID http://orcid.org/0000-0002-1836-3112
Martin KurzDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Annette FrommDepartment of Neurology, Haukeland University Hospital, Bergen, Norway.
Øyvind ØsteråsDepartment of Anaesthesia and Intensive care, Haukeland University Hospital, Bergen, Norway.
Linn Therese HagenNorwegian Air Ambulance Foundation, Bodo, Norway.
Thomas Werner LindnerRegional Centre for Emergency Medical Research and Development in Western Norway (RAKOS), Stavanger, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsResearch on the importance of the Emergency Medical Dispatch Centre (EMDC) role in reducing the time delays for patients with acute ischaemic stroke (AIS) is limited. This study aimed to analyse how Norwegian EMDCs' accurate suspicions can impact the clinical care times in this patient group.

methodsWe collected clinical care time metrics and acute reperfusion treatment data from the Norwegian Stroke Registry on patients with AIS in Western Norway who were evaluated by the EMDC and had an ambulance dispatched in 2021. In case a stroke was suspected by the EMDC, the dispatcher communicated their diagnosis suspicions to the ambulance personnel. Outcomes of interest were reperfusion treatment for AIS, prehospital and in-hospital time-to-treatment delays, and patient outcomes.

resultsOf the 1106 patients with AIS in our region, 771 (70 %) fulfilled the inclusion criteria. The EMDC suspected a stroke in 481 cases (62 %). Patients with suspected stroke experienced lower ambulance on-scene times (11 min vs 15 min; p=0.001), Emergency Medical Service prehospital times (40 min vs 49 min; p=0.021) and door-to-needle times (23 min vs 31 min; p=0.023). The EMDC stroke suspicion was associated with increased thrombolysis rates (OR 2.42 (95% CI 1.72 to 3.40)) after adjusting for age, sex, risk factors and functional status prior to the stroke event. The door-to-groin puncture times were lower for patients with a stroke suspicion who received endovascular treatment (65 min vs 85 min; p=0.004). No differences in the National Institutes of Health Stroke Scale score at the initial hospital arrival (4 vs 4; p=0.42) or in 90-day functional independence outcomes (rate of modified Rankin Scale score 0-2; 240 (61%) vs 160 (66%); p=0.24) were observed.

conclusionsAccurate EMDC recognition of stroke suspicion alerts to ambulances were associated with a reduction in time until treatment and increased intravenous thrombolysis rates. A significant proportion of patients who had a stroke were not identified by the dispatcher. Improving dispatcher stroke assessment training, tools and knowledge may reduce time delays, thus improving patient outcomes.

Indexed as

Emergency Medical DispatchEmergency Medical DispatcherIschemic StrokeReperfusionStrokeTime-to-TreatmentAgedAged, 80 and overEmergency Medical ServicesFemaleHumansMaleMiddle AgedNorwayRegistriesTime Factorsdeathemergency care systemsstroketriage

Identifiers

PMID40050006
PMCPMC12418556

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.