Evidence map›Paper›PMID 40049055›Full record

ArticleArchives of gerontology and geriatrics2025

Social context matters: Neighborhood environment as a moderator of the longitudinal relationship between edentulism and cognitive function among older adults in the United States.

Ruotong Liu, Xiang Qi, Weiyu Mao, Huabin Luo, Zhijing Xu, Bei Wu

Abstract read
In one paragraph

Article in Archives of gerontology and geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Article
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  6. Edentulism, social mobility, and cognitive aging: a life course perspective.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruotong LiuNew York University, Rory Meyers College of Nursing, New York City, NY, USA. Electronic address: liu.r@nyu.edu.
Xiang QiNew York University, Rory Meyers College of Nursing, New York City, NY, USA. Electronic address: xq450@nyu.edu.
Weiyu MaoUniversity of Nevada, Reno, School of Social Work, Reno, NV, USA. Electronic address: weiyum@unr.edu.
Huabin LuoEast Carolina University, Department of Public Health, Greenville, NC, USA. Electronic address: luoh@ecu.edu.
Zhijing XuNew York University, Rory Meyers College of Nursing, New York City, NY, USA. Electronic address: zhijing.xu@nyu.edu.
Bei WuNew York University, Rory Meyers College of Nursing, New York City, NY, USA. Electronic address: bei.wu@nyu.edu.

Funding

Rutgers-NYU Center for Asian Health Promotion and EquityP50MD017356 · NIMHD · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI WU, BEI · 2021 to 2025
$11.6M
Resource Center for Alzheimer's and Dementia Research in Asian and Pacific AmericansP30AG083257 · NIA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI William Tzu-lung Hu, DENA J SCHULMAN-GREEN · 2023 to 2026
$3.5M
Elucidating the Link Between Oral Health and Dementia Subtypes: A Multifaceted Study on the Biological Pathways and Social DeterminantsR01AG089856 · NIA · NEW YORK UNIVERSITY · PI Huabin Luo, Xiang Qi · 2024 to 2026
$2.4M
NIA NIH HHS P30 AG083257NIA NIH HHS R01 AG089856NIMHD NIH HHS P50 MD017356
6 · The paper itself

Abstract

backgroundPrevious research has shown poor oral health and neighborhood environment are both risk factors for cognitive decline among older adults. Little research has assessed the synergistic effects of poor oral health and neighborhood environment on cognitive health. This study examined whether neighborhood environment moderates the relationship between edentulism and cognitive function over time.

methodsUsing data from the Health and Retirement Study, we analyzed 9,994 adults aged 60 and older with 39,976 person-wave observations over 14 years (2006-2020). Cognitive function was measured using the modified Telephone Interview for Cognitive Status. Edentulism status was self-reported complete tooth loss. Neighborhood environment included perceived neighborhood cohesion and disorder. We used linear mixed-effect models to examine the moderation effect of neighborhood environment on the association between edentulism and cognitive function over time.

resultsEdentulous participants (22.4 %) showed an accelerated decline over time in cognitive function compared to dentate participants (β = -0.57, 95 % CI: -0.98, -0.16). The analysis revealed that neighborhood cohesion moderated the relationship between edentulism and cognitive function over time (β = 0.08, 95 % CI: 0.01, 0.15). Specifically, among individuals reporting higher neighborhood cohesion, the negative effect of edentulism on cognitive decline was attenuated. Neighborhood disorder had no significant associations with cognitive function.

conclusionsThis study demonstrates the relationship between edentulism and cognitive function varies by levels of neighborhood cohesion. The findings highlight the significance of neighborhood context in understanding the relationship between oral health and cognitive aging and suggest interventions addressing community environment may be particularly relevant for older adults with oral health challenges.

Indexed as

CognitionCognitive DysfunctionMouth, EdentulousNeighborhood CharacteristicsResidence CharacteristicsSocial EnvironmentAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedOral HealthRisk FactorsUnited StatesCognitionEdentulismNeighborhood cohesionNeighborhood disorderOral healthSocial determinants of health

Identifiers

PMID40049055
PMCPMC11968216

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.